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父母患有慢性疼痛的儿童中的物质使用情况 - HUNT 研究。

Substance use in children of parents with chronic pain - the HUNT study.

机构信息

Regional Centre for Child and Youth Mental Health and Child Welfare of Central Norway, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

Regional Centre for Child and Youth Mental Health and Child Welfare of Central Norway, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway ; Department of Child and Adolescent Psychiatry, St Olav's Hospital, Trondheim University Hospital Trondheim, Norway.

出版信息

J Pain Res. 2014 Aug 21;7:483-94. doi: 10.2147/JPR.S67819. eCollection 2014.

Abstract

PURPOSE

The aim of the present study was to investigate possible associations between parental chronic pain and smoking, alcohol, and drug use in adolescent offspring.

METHODS

Cross-sectional data from Nord-Trøndelag Health Study (HUNT 3), a Norwegian population-based health survey conducted in the period 2006-2008 was utilized. The present sample consisted of adolescents aged 13-18 years (n=3,227) for whom information was available on maternal and paternal health statuses.

RESULTS

Results from multivariable ordinal and binary logistic regression analyses, adjusting for potential confounding factors (child age, parental age, education, and organ specific illness) indicated that the estimated odds ratios (OR) for smoking (OR =1.72, 95% confidence interval [CI] [1.00, 3.05], P=0.049) and alcohol intoxication (drunkenness) (OR =1.56, 95% CI [1.05, 2.33], P=0.029) were higher for boys whose mother and father had chronic pain, compared with boys for whom neither parent had chronic pain. These associations were slightly attenuated by additional adjustment for pain-related factors, such as parental smoking and symptoms of anxiety and depression. Parental chronic pain was not significantly associated with girls' levels of substance use. There were significant interaction effects between parental chronic pain and child sex on offspring's alcohol intoxication and smoking.

CONCLUSION

The present study expands on existing knowledge and provides groundwork for preventive and specific measures targeting substance use in families burdened with parental chronic pain.

摘要

目的

本研究旨在探讨父母慢性疼痛与青少年子女吸烟、饮酒和吸毒之间可能存在的关联。

方法

本研究使用了挪威基于人群的健康调查——北特伦德拉格健康研究(HUNT3)在 2006-2008 年期间收集的横断面数据。本研究样本包括年龄在 13-18 岁的青少年(n=3227),这些青少年的母亲和父亲的健康状况信息可用。

结果

在调整了潜在混杂因素(儿童年龄、父母年龄、教育程度和器官特异性疾病)后,多变量有序和二元逻辑回归分析的结果表明,与父母均无慢性疼痛的青少年相比,母亲和父亲患有慢性疼痛的青少年吸烟(OR=1.72,95%置信区间[CI] [1.00, 3.05],P=0.049)和酒精中毒(醉酒)(OR=1.56,95% CI [1.05, 2.33],P=0.029)的估计比值(OR)更高。这些关联在进一步调整与疼痛相关的因素(如父母吸烟以及焦虑和抑郁症状)后略有减弱。父母慢性疼痛与女孩的物质使用水平无显著关联。父母慢性疼痛与子女性别之间存在显著的交互效应,对子女的酒精中毒和吸烟有影响。

结论

本研究扩展了现有知识,并为针对父母慢性疼痛家庭中子女物质使用问题的预防和具体措施奠定了基础。

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