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父母慢性疼痛与青少年和年轻成人慢性疼痛的关联:来自 HUNT 研究的家族关联数据。

Association of parental chronic pain with chronic pain in the adolescent and young adult: family linkage data from the HUNT Study.

机构信息

Department of Laboratory Medicine, Children’s and Women’s Health, Faculty of Medicine, Norwegian University of Science and Technology, 7491 Trondheim, Norway.

出版信息

JAMA Pediatr. 2013 Jan;167(1):61-9. doi: 10.1001/jamapediatrics.2013.422.

Abstract

OBJECTIVES

To examine a possible association of parental chronic pain with chronic pain in the adolescent and young adult and to explore whether a relationship could be explained by socioeconomic and psychosocial factors or may be affected by differences in family structure.

DESIGN

Unselected, population-based, cross-sectional study.

SETTING

Nord-Trøndelag County, Norway.

PARTICIPANTS

All inhabitants of Nord-Trøndelag County who were 13 years or older were invited to enroll in the study. In total, 8200 of 10 485 invitees (78.2%) participated in the investigation. Among 7913 participants in the target age group (age range, 13-18 years), 7373 (93.2%) completed the pain questions. The final study population consisted of 5370 adolescents or young adults for whom one or both parents participated in the adult survey.

MAIN OUTCOME MEASURES

The primary outcome measure was chronic nonspecific pain in adolescents and young adults, defined as pain in at least 1 location, unrelated to any known disease or injury, experienced at least once a week during the past 3 months. Chronic multisite pain was defined as chronic pain in at least 3 locations.

RESULTS

Maternal chronic pain was associated with chronic nonspecific pain and chronic multisite pain in adolescents and young adults (odds ratio, 1.5; 95% CI, 1.3-1.8). Paternal chronic pain was associated with increased odds of pain in adolescents and young adults. The odds of chronic nonspecific pain and chronic multisite pain in adolescents and young adults increased when both parents reported pain. Adjustments for socioeconomic and psychosocial factors did not change the results, although differences in family structure did. Among offspring living primarily with their mothers, clear associations were observed between maternal pain and pain in adolescents and young adults, but no association was found with paternal pain.

CONCLUSIONS

Parental chronic pain is associated with chronic nonspecific pain and especially with chronic multisite pain in adolescents and young adults. Family structure influences the relationship, indicating that family pain models and shared environmental factors are important in the origin of chronic pain.

摘要

目的

研究父母慢性疼痛与青少年和年轻成人慢性疼痛之间可能存在的关联,并探讨这种关联是否可以用社会经济和心理社会因素来解释,或者是否可能受到家庭结构差异的影响。

设计

未选择、基于人群的横断面研究。

地点

挪威特隆赫姆郡。

参与者

邀请了特隆赫姆郡所有 13 岁及以上的居民参加这项研究。共有 10485 名邀请者中的 8200 人(78.2%)参加了调查。在目标年龄组(年龄范围 13-18 岁)的 7913 名参与者中,有 7373 人(93.2%)完成了疼痛问题的调查。最终的研究人群包括 5370 名青少年或年轻人,他们的父母中有一人或两人参加了成人调查。

主要结果测量

青少年和年轻成人的主要结果是慢性非特异性疼痛,定义为至少在 1 个部位疼痛,与任何已知的疾病或损伤无关,在过去 3 个月中每周至少出现 1 次。慢性多部位疼痛定义为至少 3 个部位的慢性疼痛。

结果

母亲的慢性疼痛与青少年和年轻成人的慢性非特异性疼痛和慢性多部位疼痛有关(比值比,1.5;95%置信区间,1.3-1.8)。父亲的慢性疼痛与青少年和年轻成人疼痛的几率增加有关。当父母双方都报告疼痛时,青少年和年轻成人发生慢性非特异性疼痛和慢性多部位疼痛的几率增加。尽管家庭结构存在差异,但调整社会经济和心理社会因素并没有改变结果。在主要与母亲一起生活的子女中,母亲的疼痛与青少年和年轻成人的疼痛之间存在明显的关联,但与父亲的疼痛无关。

结论

父母的慢性疼痛与青少年和年轻成人的慢性非特异性疼痛,特别是慢性多部位疼痛有关。家庭结构影响这种关系,表明家庭疼痛模型和共同的环境因素在慢性疼痛的起源中很重要。

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