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Polymorphisms in FTO, TMEM18 and PCSK1 are associated with BMI in southern Chinese population.

作者信息

Chen Jie, Yang Mei, Zhao Kehui, Xu Aimin, Huang Qingyang

机构信息

College of Life Sciences, Central China Normal University, Wuhan 430079, People's Republic of China.

出版信息

J Genet. 2014 Aug;93(2):509-12.

PMID:25189249
Abstract
摘要

相似文献

1
Polymorphisms in FTO, TMEM18 and PCSK1 are associated with BMI in southern Chinese population.FTO、TMEM18和PCSK1基因多态性与中国南方人群的体重指数相关。
J Genet. 2014 Aug;93(2):509-12.
2
Common variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 show evidence of association with adult obesity in the Greek population.FTO、MC4R、TMEM18、PRL、AIF1 和 PCSK1 中的常见变异与希腊人群的成人肥胖有关。
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3
Genes and lifestyle factors in obesity: results from 12,462 subjects from MONICA/KORA.肥胖相关基因与生活方式因素：来自 MONICA/KORA 研究的 12462 例受试者结果。
Int J Obes (Lond). 2010 Oct;34(10):1538-45. doi: 10.1038/ijo.2010.79. Epub 2010 Apr 13.
4
Variations in the obesity genes FTO, TMEM18 and NRXN3 influence the vulnerability of children to weight gain induced by short sleep duration.肥胖基因 FTO、TMEM18 和 NRXN3 的变异影响儿童因睡眠不足而体重增加的易感性。
Int J Obes (Lond). 2013 Feb;37(2):182-7. doi: 10.1038/ijo.2012.27. Epub 2012 Mar 6.
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First investigation of two obesity-related loci (TMEM18, FTO) concerning their association with educational level as well as income: the MONICA/KORA study.首次探究两个与肥胖相关的基因座（TMEM18、FTO）与教育水平和收入的关联：MONICA/KORA 研究。
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β2-adrenergic receptor Thr164Ile polymorphism, obesity, and diabetes: comparison with FTO, MC4R, and TMEM18 polymorphisms in more than 64,000 individuals.β2-肾上腺素能受体 Thr164Ile 多态性、肥胖和糖尿病：与超过 64000 个人的 FTO、MC4R 和 TMEM18 多态性的比较。
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Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes.FTO 和 TMEM18 附近的多态性与 2 型糖尿病相关，并使糖尿病的发病年龄提前。
Gene. 2013 Sep 25;527(2):462-8. doi: 10.1016/j.gene.2013.06.079. Epub 2013 Jul 13.
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The association of common variants in PCSK1 with obesity: a HuGE review and meta-analysis.前蛋白转化酶枯草溶菌素1（PCSK1）常见变异与肥胖的关联：一项HuGE综述及荟萃分析
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The obesity-related polymorphism PCSK1 rs6235 is associated with essential hypertension in the Han Chinese population.肥胖相关多态性 PCSK1 rs6235 与汉族人群的原发性高血压相关。
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本文引用的文献

1
Functional relevance of genes implicated by obesity genome-wide association study signals for human adipocyte biology.肥胖全基因组关联研究信号所涉及基因在人类脂肪细胞生物学中的功能相关性。
Diabetologia. 2013 Feb;56(2):311-22. doi: 10.1007/s00125-012-2773-0. Epub 2012 Nov 16.
2
Beyond the fourth wave of genome-wide obesity association studies.超越第四波全基因组肥胖关联研究。
Nutr Diabetes. 2012 Jul 30;2(7):e37. doi: 10.1038/nutd.2012.9.
3
PCSK1 rs6232 is associated with childhood and adult class III obesity in the Mexican population.
PCSK1 rs6232 与墨西哥人群中的儿童和成人 III 级肥胖有关。
PLoS One. 2012;7(6):e39037. doi: 10.1371/journal.pone.0039037. Epub 2012 Jun 21.
4
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians.FTO 基因变异与东亚和南亚 96551 人肥胖和 2 型糖尿病风险的关联。
Diabetologia. 2012 Apr;55(4):981-95. doi: 10.1007/s00125-011-2370-7. Epub 2011 Nov 23.
5
Study of eight GWAS-identified common variants for association with obesity-related indices in Chinese children at puberty.研究 8 个与青春期中国儿童肥胖相关指标关联的 GWAS 鉴定的常见变异。
Int J Obes (Lond). 2012 Apr;36(4):542-7. doi: 10.1038/ijo.2011.218. Epub 2011 Nov 15.
6
Common variants of FTO and the risk of obesity and type 2 diabetes in Indians.FTO 常见变异与印度人肥胖和 2 型糖尿病风险。
J Hum Genet. 2011 Oct;56(10):720-6. doi: 10.1038/jhg.2011.87. Epub 2011 Aug 4.
7
Common variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 show evidence of association with adult obesity in the Greek population.FTO、MC4R、TMEM18、PRL、AIF1 和 PCSK1 中的常见变异与希腊人群的成人肥胖有关。
Obesity (Silver Spring). 2012 Feb;20(2):389-95. doi: 10.1038/oby.2011.177. Epub 2011 Jun 30.
8
Implication of genetic variants near TMEM18, BCDIN3D/FAIM2, and MC4R with coronary artery disease and obesity in Chinese: a angiography-based study.TMEM18、BCDIN3D/FAIM2 和 MC4R 附近的遗传变异与中国冠心病和肥胖的关系：一项基于血管造影的研究。
Mol Biol Rep. 2012 Feb;39(2):1739-44. doi: 10.1007/s11033-011-0914-z. Epub 2011 May 28.
9
Influence of common variants in FTO and near INSIG2 and MC4R on growth curves for adiposity in African- and European-American youth.FTO 和 INSIG2 及 MC4R 附近常见变异对非裔美国和欧洲裔美国青少年肥胖生长曲线的影响。
Eur J Epidemiol. 2011 Jun;26(6):463-73. doi: 10.1007/s10654-011-9583-4. Epub 2011 May 5.
10
Association of genetic variants for susceptibility to obesity with type 2 diabetes in Japanese individuals.日本人群中肥胖易感性的遗传变异与 2 型糖尿病的关联。
Diabetologia. 2011 Jun;54(6):1350-9. doi: 10.1007/s00125-011-2086-8. Epub 2011 Mar 3.