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在中国棕果蝠中鉴定出一种新型正嗜肝DNA病毒。

Identification of a novel Orthohepadnavirus in pomona roundleaf bats in China.

作者信息

He Biao, Zhang Fuqiang, Xia Lele, Hu Tingsong, Chen Gang, Qiu Wei, Fan Quanshui, Feng Ye, Guo Huancheng, Tu Changchun

机构信息

Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, 666 Liuying West Road, Jingyue Economic Development Zone, Changchun, 130122, People's Republic of China.

出版信息

Arch Virol. 2015 Jan;160(1):335-7. doi: 10.1007/s00705-014-2222-0. Epub 2014 Sep 7.

Abstract

Bats in Myanmar, Gabon, and Panama have been found to harbor diverse hepadnaviruses. Here, we report a novel hepadnavirus in 4 of 20 pomona roundleaf bats from Yunnan province, China. This virus contains 3,278 nucleotides (nt) in the full circularized genome, with four predicted open frames (ORFs) reading in the same direction. Full genomic sequence comparisons and evolutionary analysis indicate that this virus is a member of a new species within the genus Orthohepadnavirus.

摘要

在缅甸、加蓬和巴拿马的蝙蝠中发现了多种嗜肝DNA病毒。在此,我们报告在中国云南省20只棕果蝠中有4只携带一种新型嗜肝DNA病毒。该病毒的完整环状基因组包含3278个核苷酸(nt),有四个预测的开放阅读框(ORF),且阅读方向相同。全基因组序列比较和进化分析表明,该病毒是正嗜肝DNA病毒属内一个新物种的成员。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7379/7087111/26e6a9200156/705_2014_2222_Fig1_HTML.jpg

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