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肾副肿瘤性血管炎并发肺腺癌

Renal paraneoplastic vasculitis complicating lung adenocarcinoma.

作者信息

Dhaou Besma Ben, Boussema Fatma, Aydi Zohra, Ketari Sonia, Baili Lilia, Moussa Fatma Ben, Rokbani Lilia

机构信息

Internal Medicine Department, Habib Thameur Hospital, Tunis, Tunisia.

出版信息

Saudi J Kidney Dis Transpl. 2014 Sep;25(5):1065-7. doi: 10.4103/1319-2442.139942.

Abstract

Renal paraneoplastic vasculitis (RNPV) is rare. It can be revealed by glomerulonephritis, microaneurysms or renal failure. RPNV may precede the onset of the primary tumor, and treatment and prognosis depend on the etiology (primary tumor). A 54-year-old man who had a primary lung adenocarcinoma was admitted for nephrotic syndrome. The investigations revealed RNPV. The patient was treated with corticosteroids at high dose and cyclophosphamide with improvement of the renal condition; however, the patient died from worsening of his pulmonary neoplasia.

摘要

肾副肿瘤性血管炎(RNPV)较为罕见。它可表现为肾小球肾炎、微动脉瘤或肾衰竭。RNPV可能在原发性肿瘤发病之前出现,其治疗和预后取决于病因(原发性肿瘤)。一名患有原发性肺腺癌的54岁男性因肾病综合征入院。检查发现为RNPV。该患者接受了大剂量皮质类固醇和环磷酰胺治疗,肾脏状况有所改善;然而,患者最终因肺部肿瘤恶化而死亡。

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