Hashim Al-Saedi Ali J, Jameel Nawar S, Qais Ali, Kareem Abdul Hakeem A, Mohssen Talib S
Department of Nephrology, Faculty of Medicine, Al Kindy College of Medicine, Baghdad, Iraq.
Saudi J Kidney Dis Transpl. 2014 Sep;25(5):1098-104. doi: 10.4103/1319-2442.139964.
Cardiovascular complications including abdominal aortic calcification significantly affect the mortality and morbidity in patients on a hemodialysis (HD) program. The objective of this study is to find the frequency of abdominal aortic calcification in patients on regular HD and to evaluate the effect of parameters on frequency and severity of abdominal aortic calcification. Fifty-four patients with end-stage renal disease on regular HD were studied from January 2011 to December 2011 to evaluate abdominal aortic calcification by plain abdominal X-ray. The study showed that 10 (18.5%) patients had abdominal aortic calcification. Only one (1.9%) had grade 3 calcification and among the remaining, five (9.3%) patients had grade 1 and four (7.4%), grade 2. There was a statistically significant difference (P <0.05) in the means of serum cholesterol among those with and without abdominal aortic calcification. Hypertension was noticed in most patients with abdominal aortic calcification. The frequency of abdominal aortic calcification is directly related to age and duration of dialysis. The only biochemical parameter with a statistically significant effect was serum cholesterol.
包括腹主动脉钙化在内的心血管并发症显著影响接受血液透析(HD)治疗的患者的死亡率和发病率。本研究的目的是确定接受常规HD治疗的患者腹主动脉钙化的发生率,并评估各项参数对腹主动脉钙化发生率和严重程度的影响。对2011年1月至2011年12月期间接受常规HD治疗的54例终末期肾病患者进行了研究,通过腹部X线平片评估腹主动脉钙化情况。研究显示,10例(18.5%)患者存在腹主动脉钙化。只有1例(1.9%)为3级钙化,其余患者中,5例(9.3%)为1级钙化,4例(7.4%)为2级钙化。腹主动脉钙化患者与无腹主动脉钙化患者的血清胆固醇均值存在统计学显著差异(P<0.05)。大多数腹主动脉钙化患者存在高血压。腹主动脉钙化的发生率与年龄和透析时间直接相关。唯一具有统计学显著影响的生化参数是血清胆固醇。