Song Seungjun, Lee Seung Hyun, Lee Hyung Chae, Youn Young-Nam, Chang Byung-Chul, Yoo Kyung-Jong, Kim Jong Gun, Lee Sak
Division of Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Yonsei University Health System, Seoul, Republic of Korea.
J Card Surg. 2015 Jan;30(1):7-12. doi: 10.1111/jocs.12445. Epub 2014 Sep 5.
Acute kidney injury (AKI) is a common complication after cardiac surgery. Associations between the time interval (TI) from preoperative coronary angiography (CAG) to cardiac surgery have been investigated, although with conflicting results.
We evaluated data collected from a retrospective review of consecutive patients who underwent preoperative CAG and heart valve surgery at our institution between September 2008 and February 2013. A total of 426 patients met the study criteria. Patients were divided into two groups according to the length of time between preoperative CAG and valve surgery: within one day (group A) or longer than one day (group B). Logistic regression was applied to analyze the relationships between TI and postoperative AKI.
Of 426 patients, 140 (33%) underwent CAG on preoperative day 1, while 286 (67%) underwent CAG on preoperative day 2 or sooner. AKI occurred in 19 (13.6%) patients in group A and in 35 (12.2%) patients in group B (p = 0.70). CAG on preoperative day 1 was not associated an increased risk of AKI relative to CAG on preoperative day 2 or sooner (p = 0.49; odds ratio, 1.26; 95% CI, 0.66 to 2.41).
Preoperative CAG within one day of elective heart valve surgery is not associated with an increase in postoperative AKI in patients with normal renal function.
急性肾损伤(AKI)是心脏手术后常见的并发症。术前冠状动脉造影(CAG)至心脏手术的时间间隔(TI)之间的关联已得到研究,尽管结果相互矛盾。
我们评估了从2008年9月至2013年2月在本机构接受术前CAG和心脏瓣膜手术的连续患者的回顾性数据。共有426例患者符合研究标准。根据术前CAG与瓣膜手术之间的时间长短将患者分为两组:一天内(A组)或超过一天(B组)。应用逻辑回归分析TI与术后AKI之间的关系。
426例患者中,140例(33%)在术前第1天接受CAG,而286例(67%)在术前第2天或更早接受CAG。A组19例(13.6%)患者发生AKI,B组35例(12.2%)患者发生AKI(p = 0.70)。与术前第2天或更早接受CAG相比,术前第1天接受CAG与AKI风险增加无关(p = 0.49;优势比,1.26;95%可信区间,0.66至2.41)。
对于肾功能正常的患者,择期心脏瓣膜手术前一天内进行术前CAG与术后AKI增加无关。