患有成骨不全症和桥本甲状腺炎的同卵青春期双胞胎中的甲状腺乳头状癌：存在遗传联系吗？
Papillary thyroid cancer in identical adolescent twins with osteogenesis imperfecta and Hashimoto's thyroiditis: is there a genetic link?
作者信息
Diegidio Paul, Kolok Damon, Brown Whitney, Camps Juan I
机构信息
Department of Surgery, University of South Carolina, Columbia, South Carolina, USA.
出版信息
Am Surg. 2014 Sep;80(9):849-50.
PMID:25197868
Abstract
The relationship between Hashimoto's thyroiditis (HT) and papillary thyroid cancer (PTC) remains controversial. Researchers have identified multiple genes that could put patients with HT at risk for PTC. None are related to osteogenesis imperfecta (OI). We present identical twin sisters with OI who developed PTC in the setting HT.
摘要
桥本甲状腺炎（HT）与甲状腺乳头状癌（PTC）之间的关系仍存在争议。研究人员已鉴定出多个可能使HT患者面临PTC风险的基因。但均与成骨不全症（OI）无关。我们报告了一对患有OI的同卵双胞胎姐妹，她们在HT背景下发生了PTC。
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