Matesa-Anić Dubravka, Matesa Neven, Dabelić Nina, Kusić Zvonko
Department of Otorhinolaryngology, Thalassotherapia Special Hospital for Medical Rehabilitation, Crikvenica, Croatia.
Acta Clin Croat. 2009 Mar;48(1):9-12.
The aim of the study was to determine the incidence of coexistence of papillary carcinoma and Hashimoto's thyroiditis in cytologic material. Cytologic findings were collected from 10508 patients that underwent ultrasound-guided fine needle aspiration cytology (FNAC) of the thyroid. Hashimoto's thyroiditis was found in 2156 (20.5%) and papillary carcinoma in 269 (2.6%) of 10508 patients with FNAC, whereas both Hashimoto's thyroiditis and papillary carcinoma were present in 42 (0.4%) patients. Among patients with FNAC diagnosis of Hashimoto's thyroiditis, the prevalence of papillary carcinoma was 1.9%. Among patients with FNAC diagnosis of papillary carcinoma, the prevalence of Hashimoto's thyroiditis was 15.6%. There was no statistically significant association between the presence of papillary carcinoma and Hashimoto's thyroiditis in patients undergoing FNAC (p=0.0522). In conclusion, in a large series of patients, the incidence of Hashimoto's thyroiditis and papillary carcinoma coexistence in cytologic material was 0.4%. There was no statistically significant relationship between Hashimoto's thyroiditis and papillary carcinoma in cytologic material.
本研究的目的是确定细胞学材料中乳头状癌与桥本甲状腺炎并存的发生率。从10508例接受甲状腺超声引导下细针穿刺细胞学检查(FNAC)的患者中收集细胞学检查结果。在10508例行FNAC检查的患者中,发现2156例(20.5%)患有桥本甲状腺炎,269例(2.6%)患有乳头状癌,而42例(0.4%)患者同时患有桥本甲状腺炎和乳头状癌。在FNAC诊断为桥本甲状腺炎的患者中,乳头状癌的患病率为1.9%。在FNAC诊断为乳头状癌的患者中,桥本甲状腺炎的患病率为15.6%。接受FNAC检查的患者中,乳头状癌的存在与桥本甲状腺炎之间无统计学显著关联(p=0.0522)。总之,在一大系列患者中,细胞学材料中桥本甲状腺炎与乳头状癌并存的发生率为0.4%。细胞学材料中桥本甲状腺炎与乳头状癌之间无统计学显著关系。