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在胃食管反流病患者中,患者症状与客观测量指标之间的相关性较差。

Patient symptoms correlate poorly with objective measures among patients with gastroesophageal reflux disease.

作者信息

Levy Salomon, Plymale Margaret, Davenport Daniel L, Moreno Ponte Oscar I, Roth J Scott

机构信息

Department of Surgery, University of Kentucky College of Medicine, Lexington, Kentucky, USA.

出版信息

Am Surg. 2014 Sep;80(9):901-5.

PMID:25197878
Abstract

Presentation of gastroesophageal reflux disease (GERD) varies among patients. To attempt to understand the patient's perception of the severity of their reflux symptoms, we developed a questionnaire on which patients rated symptom severity at each office visit. After receiving Institutional Review Board approval, we retrospectively reviewed patient charts of all patients seen by one surgeon for GERD symptoms and/or presence of hiatal hernia (HH) from September 2012 to April 2013. Data from patient questionnaires combined with objective findings from subsequent or prior workup and eventual operative information were recorded. A total of 144 questionnaires were reviewed from 108 patients. Frequencies were calculated for categorical variables. Patients were divided into four categories based on size of the HH on the endoscopic report; 10 patients had no HH, 15 had small HH, 20 had medium HH, and 31 patients had large HH. Size of HH was not available for three patients. Pre- and postoperative questionnaire responses were obtained for 15 patients. A combined reflux score was calculated using the median for each symptom. Patient perception of severity of symptoms does not necessarily predict presence of pathological reflux or HH nor is there a perfect combination of symptoms to predict the presence of pathological reflux or HH based on our sample. The workup of this pathology must be comprehensive, and the confirmation of reflux is imperative when the diagnosis is unclear.

摘要

胃食管反流病(GERD)在患者中的表现各不相同。为了试图了解患者对其反流症状严重程度的认知,我们编制了一份问卷,让患者在每次门诊就诊时对症状严重程度进行评分。在获得机构审查委员会批准后,我们回顾性地查阅了2012年9月至2013年4月期间由一位外科医生诊治的所有因GERD症状和/或存在食管裂孔疝(HH)的患者的病历。记录了来自患者问卷的数据,以及后续或先前检查的客观结果和最终的手术信息。共对108例患者的144份问卷进行了审查。计算分类变量的频率。根据内镜报告中HH的大小将患者分为四类;10例患者无HH,15例有小HH,20例有中HH,31例患者有大HH。3例患者的HH大小信息缺失。获得了15例患者术前和术后的问卷回复。使用每种症状的中位数计算综合反流评分。基于我们的样本,患者对症状严重程度的认知不一定能预测病理性反流或HH的存在,也不存在能预测病理性反流或HH存在的完美症状组合。对这种病理情况的检查必须全面,当诊断不明确时,必须确认反流情况。

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