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[各种红细胞抗原与血液系统疾病之间的关系]

[Relationship between various erythrocyte antigens and hematologic disorders].

作者信息

Arevalo C, Gajardo M, León A, Espinoza E, Marín F

出版信息

Rev Med Chil. 1989 Nov;117(11):1221-6.

PMID:2519795
Abstract

The antigen pattern pertaining to the ABO (A, B, AB, O (H)), Rh (D, C, c, E, e), Duffy (Fya and b), Kell (K, k) and MNS (M, N) systems were determined in 144 patients between 1 and 74 years of age who had leukemia, lymphoma or myeloma. An association of phenotype Fy (a-b+) with acute lymphatic leukemia and phenotype NN with chronic myeloid leukemia was demonstrated (p less than 0.05, chi sq). Other associations were statistically not significant. Thus, a susceptibility of the aforementioned phenotype patterns to the type of leukemia described is suggested by these findings.

摘要

对144例年龄在1至74岁之间患有白血病、淋巴瘤或骨髓瘤的患者,测定了与ABO(A、B、AB、O(H))、Rh(D、C、c、E、e)、达菲(Fya和b)、凯尔(K、k)及MNS(M、N)血型系统相关的抗原模式。结果显示,Fy(a-b+)表型与急性淋巴细胞白血病、NN表型与慢性髓细胞白血病之间存在关联(p<0.05,卡方检验)。其他关联在统计学上无显著意义。因此,这些发现提示上述表型模式对所描述的白血病类型具有易感性。

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