Allen Valerie A, Takashima Yoko, Nayak Seema, Manahan Kelly J, Geisler John P
†Division of Gynecologic Oncology *Department of Obstetrics and Gynecology, University of Toledo College of Medicine and Life Sciences, Toledo, OH.
Am J Clin Oncol. 2017 Apr;40(2):175-177. doi: 10.1097/COC.0000000000000119.
The objective was to determine how often peritoneal cytology is positive for malignancy in women with known ovarian cancer. Knowing this fact would help determine the usefulness of diagnostic paracentesis.
Records of all women diagnosed with invasive epithelial ovarian cancer from 2004 to 2012 were examined to correlate presence of ascites, cytologic, and pathologic findings.
A total of 313 patients were included in analysis. A total of 210 of 313 patients (67.1%) with ascites had cytology positive for malignancy. This left 103 patients with ascites and cancer without malignant cells found in the ascites removed at the time of surgery.
Except in a few cases, paracentesis is not recommended for the diagnosis of ovarian cancer because of the potential spreading of cancer. Furthermore, with only just over two thirds of cases of known cancer and ascites having cytology positive for malignancy, the value of paracentesis for diagnosis of ovarian cancer is minimal.
本研究旨在确定已知患有卵巢癌的女性中，腹膜细胞学检查恶性肿瘤呈阳性的频率。了解这一情况将有助于确定诊断性腹腔穿刺术的实用性。
对2004年至2012年期间所有被诊断为侵袭性上皮性卵巢癌的女性患者记录进行检查，以关联腹水、细胞学和病理学检查结果。
共有313例患者纳入分析。313例有腹水的患者中，共有210例（67.1%）细胞学检查恶性肿瘤呈阳性。这使得103例有腹水且患有癌症的患者在手术时所抽取的腹水中未发现恶性细胞。
除少数情况外，由于存在癌症扩散的可能性，不建议采用腹腔穿刺术诊断卵巢癌。此外，已知患有癌症且有腹水的病例中，只有略超过三分之二的病例细胞学检查恶性肿瘤呈阳性，因此腹腔穿刺术对卵巢癌的诊断价值极小。
