Dailey Roger A, Marx Douglas P, Ahn Eric S
*Division of Oculofacial Plastic Surgery, Department of Ophthalmology, Casey Aesthetic Facial Surgery Center, Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, U.S.A.; and †Division of Ophthalmic Plastic, Lacrimal, and Orbital Surgery, Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, U.S.A.
Ophthalmic Plast Reconstr Surg. 2015 May-Jun;31(3):233-41. doi: 10.1097/IOP.0000000000000275.
To describe clinical outcomes of patients receiving porcine dermal matrix implants for lower eyelid retraction repair.
A retrospective review of all patients who underwent lower eyelid retraction repair with porcine dermal matrix implantation between June 2007 and July 2013 at a tertiary care center was conducted. Patient demographics, procedure(s) performed, preoperative and postoperative marginal reflex distance, inferior scleral show, and complications were reviewed. Patients with a prior history of lower eyelid surgery were excluded. The study is Health Insurance Portability and Accountability Act compliant, institutional review board approved, and adherent to the Declaration of Helsinki.
One hundred patients (160 eyelids) received porcine dermal collagen implants. Fifty-six patients had thyroid eye disease, 23 had midface descent, 10 had seventh nerve palsies, and 11 had other etiologies of retraction. The average preoperative marginal reflex distance was 7.64 mm in the OD and 7.17 mm in the OS, compared with 6.40 mm in the OD and 6.22 mm in the OS postoperatively. The average preoperative inferior scleral show was 2.04 in the OD and 1.70 in the OS compared with 0.81 mm in the OD and 0.65 mm in the OS postoperatively. Follow up ranged from 1.46 to 66.04 months, with an average of 14.06 months and median of 8.84 months. Nineteen eyelids had implant-related complications: 7 with cyst formation, 7 with exposure/rejection, 2 with long-term pain, 2 with transient inflammation, and 3 with irregular implant contour.
Porcine dermal matrix implants provide reliable support, integration, and function in lower eyelid retraction repair without significant resorption or complications in the majority of patients.
描述接受猪真皮基质植入物修复下睑退缩患者的临床结局。
对2007年6月至2013年7月在一家三级医疗中心接受猪真皮基质植入修复下睑退缩的所有患者进行回顾性研究。回顾了患者的人口统计学资料、所进行的手术、术前和术后的边缘反射距离、下巩膜显露情况以及并发症。排除有下睑手术史的患者。本研究符合《健康保险流通与责任法案》，经机构审查委员会批准，并遵循《赫尔辛基宣言》。
一百名患者（160只眼睑）接受了猪真皮胶原植入物。56名患者患有甲状腺眼病，23名患者有中面部下垂，10名患者有面神经麻痹，11名患者有其他退缩病因。术前平均边缘反射距离右眼为7.64毫米，左眼为7.17毫米，术后右眼为6.40毫米，左眼为6.22毫米。术前平均下巩膜显露右眼为2.04，左眼为1.70，术后右眼为0.81毫米，左眼为0.65毫米。随访时间为1.46至66.04个月，平均为14.06个月，中位数为8.84个月。19只眼睑出现与植入物相关的并发症：7只出现囊肿形成，7只出现暴露/排斥反应，2只出现长期疼痛，2只出现短暂炎症，3只出现植入物轮廓不规则。
猪真皮基质植入物在下睑退缩修复中提供可靠的支撑、整合和功能，大多数患者无明显吸收或并发症。
