[肿瘤正电子发射断层显像]

[Oncology PET imaging].

作者信息

Inubushi Masayuki

出版信息

Igaku Butsuri. 2014;34(1):3-9.

PMID:25199271

Abstract

At the beginning of this article, likening medical images to "Where is Waldo?" I indicate the concept of diagnostic process of PET/CT imaging, so that medical physics specialists could understand the role of each imaging modality and infer our distress for image diagnosis. Then, I state the present situation of PET imaging and the basics (e.g. health insurance coverage, clinical significance, principle, protocol, and pitfall) of oncology FDG-PET imaging which accounts for more than 99% of all clinical PET examinations in Japan. Finally, I would like to give a wishful prospect of oncology PET that will expand to be more cancer-specific in order to assess therapeutic effects of emerging molecular targeted drugs targeting the "hallmarks of cancer".

摘要

在本文开头，我将医学影像比作“威利在哪里？”，以此阐述PET/CT成像诊断过程的概念，以便医学物理专家能够理解每种成像方式的作用，并体会我们在图像诊断方面的困扰。然后，我阐述了PET成像的现状以及肿瘤学FDG-PET成像的基础知识（如医保覆盖范围、临床意义、原理、方案及陷阱），在日本，肿瘤学FDG-PET成像占所有临床PET检查的99%以上。最后，我想对肿瘤学PET的前景做一个美好的展望，即它将发展得更具癌症特异性，从而评估针对“癌症特征”的新型分子靶向药物的治疗效果。