[黑人儿童的客观验光：环喷托酯与托吡卡胺联合使用，是阿托品的可靠替代方法？]

[Objective refraction in black children: cyclopentolate and tropicamide combination, a reliable alternative to atropine?].

作者信息

Ka A M, De Medeiros M E, Sow A S, Ndiaye P A, Weladji C, Diallo H M, Wane A M, Diagne J P, Kane A, Ndiaye J M M, Ndoye Roth P A, Ba E A, Ndiaye M R

机构信息

Centre d'ophtalmologie de l'hôpital Abass-Ndao, B 45831 Dakar-Fann, Sénégal.

出版信息

J Fr Ophtalmol. 2014 Nov;37(9):689-94. doi: 10.1016/j.jfo.2014.05.005. Epub 2014 Sep 6.

DOI:10.1016/j.jfo.2014.05.005

PMID:25199485

Abstract

INTRODUCTION

Cycloplegia allows for an objective refraction in children. Atropine is the gold standard but causes prolonged blurred vision. Cyclopentolate is less effective but less disabling. Tropicamide is a weak cycloplegic. The purpose of this study was to evaluate a cyclopentolate and tropicamide combination (CTA) versus atropine for refraction in black children.

MATERIALS AND METHODS

We performed a prospective study between October 2011 and July 2012 on all children seen in consultation. Objective refraction was performed after cycloplegia with cyclopentolate 0.5% combined with tropicamide 0.5%, and then after cycloplegia with atropine.

RESULTS

Thirty-three patients were recruited, 14 boys and 19 girls. The average age was 9.9 years. The mean age of the patients was 9.9 years. Astigmatism was found in 96.9% of cases. It was 1.34±1.32 diopters with CTA and 1.35±1.22 diopters with atropine. The mean axis was 98.15 and 99.8, respectively. Hyperopia and myopia were found in 39 and 27 eyes, respectively with ACT (average 1.73 and 5.37 diopters), and in 41 and 19 eyes with atropine (average 2.06 and 6.11 diopters).

DISCUSSION

There is a good correlation of results with regards to cylindrical and spherical refractive error between the two protocols. Atropine is the best cycloplegic, however ACT provides reliable results.

CONCLUSION

The cyclopentolate-tropicamide combination is satisfactory for routine cycloplegia in children.

摘要

引言

睫状肌麻痹有助于对儿童进行客观验光。阿托品是金标准，但会导致长时间视力模糊。环喷托酯效果较差，但对视力的影响较小。托吡卡胺是一种弱睫状肌麻痹剂。本研究的目的是评估环喷托酯和托吡卡胺联合用药（CTA）与阿托品在黑人儿童验光中的效果。

材料与方法

我们在2011年10月至2012年7月期间对所有前来咨询的儿童进行了一项前瞻性研究。分别用0.5%环喷托酯与0.5%托吡卡胺联合用药以及阿托品进行睫状肌麻痹后进行客观验光。

结果

招募了33名患者，14名男孩和19名女孩。平均年龄为9.9岁。96.9%的病例发现有散光。CTA组散光为1.34±1.32屈光度，阿托品组为1.35±1.22屈光度。平均轴位分别为98.15和99.8。CTA组分别有39只眼和27只眼为远视和近视（平均1.73和5.37屈光度），阿托品组分别有41只眼和19只眼为远视和近视（平均2.06和6.11屈光度）。