Shimauchi Tsukasa, Yamaura Ken, Sugibe Sayaka, Hoka Sumio
Department of Anesthesiology and Critical Care, Kyushu University Hospital, Fukuoka, Japan.
Operating Rooms, Kyushu University Hospital, Fukuoka, Japan.
Acta Anaesthesiol Taiwan. 2014 Sep;52(3):146-8. doi: 10.1016/j.aat.2014.02.005. Epub 2014 Sep 8.
A 54-year-old patient with Becker muscular dystrophy and dilated cardiomyopathy underwent laparoscopic cholecystectomy under total intravenous anesthesia. Muscle relaxation was induced by rocuronium (0.4 mg/kg body weight) under train-of-four (TOF) ratio monitoring. The TOF ratio was 0 at intubation, and 0.2 at the end of surgery. Residual muscle relaxant activity was successfully reversed by sugammadex (2 mg/kg body weight) without any hemodynamic adverse effects (TOF ratio 1.0 at extubation). The clinical and hemodynamic findings suggest that sugammadex can be safely used in patients with Becker muscular dystrophy and dilated cardiomyopathy.
