乳腺癌：唑来膦酸——不仅仅是一种骨药物。
Breast cancer: Zoledronic acid--more than just a bone drug.
机构信息
University of Pittsburgh Cancer Institute, UPMC Cancer Pavilion, 5150 Center Avenue, Pittsburgh, PA 15232, USA.
出版信息
Nat Rev Clin Oncol. 2014 Oct;11(10):564-5. doi: 10.1038/nrclinonc.2014.152. Epub 2014 Sep 9.
PMID:25200411
Abstract
Several clinical trials have investigated the antitumour effect of bisphosphonates when used as adjuvant treatment for early stage breast cancer. Among these, the results of the AZURE trial, although negative,highlight the potential benefit of treatment with zoledronic acid in postmenopausal women with high-risk early stage breast cancer.
摘要
几项临床试验研究了双膦酸盐作为早期乳腺癌辅助治疗的抗肿瘤作用。其中，AZURE 试验的结果虽然为阴性，但强调了唑来膦酸治疗绝经后高危早期乳腺癌患者的潜在获益。
Zotero 插件