Hume-Lee Transplant Center of Virginia Commonwealth University, Richmond, VA 23298, USA.
Nat Rev Gastroenterol Hepatol. 2014 Oct;11(10):580-1. doi: 10.1038/nrgastro.2014.161. Epub 2014 Sep 9.
Although clinicians instinctively recognise acute-on-chronic liver failure (ACLF), heretofore we have had no way of accurately studying the syndrome, as no definition of this entity existed. A consortium of European centres has finally offered a definition of ACLF and proposed a prognostic index based upon easily obtained features of patients with decompensated cirrhosis.
虽然临床医生本能地认识到慢加急性肝衰竭（ACLF），但迄今为止，由于我们还没有这种疾病的定义，因此一直无法对其进行准确的研究。一个由欧洲中心组成的联合会终于提出了 ACLF 的定义，并提出了一个基于失代偿性肝硬化患者容易获得的特征的预后指数。
