Tonidandel A, Booth J, D'Angelo R, Harris L, Tonidandel S
Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Int J Obstet Anesth. 2014 Nov;23(4):357-64. doi: 10.1016/j.ijoa.2014.05.004. Epub 2014 Jun 4.
In 1993, Hood and Dewan published the results of a trial comparing obstetric and anesthetic outcomes of 117 morbidly obese parturients with matched controls. The authors demonstrated a higher initial epidural anesthesia failure rate, a higher cesarean delivery rate and an increased risk of obstetric complications. We replicated the previous study to provide updated information on outcomes in the morbidly obese pregnant population. We hypothesized that morbidly obese women would still have higher complication and failure rates compared to matched controls and that general anesthesia would be less commonly used than in the previous study.
The medical records of 230 patients weighing >136 kg (300 pounds) were compared to matched controls: the next patient delivered by the same obstetrician with a weight <113 kg (250 pounds).
The mean body mass index of the morbidly obese group was 53.4 ± 6.6 kg/m² [corrected] compared to 31.1±5.4 kg/m2 in the control group. Fifty percent of morbidly obese women required cesarean delivery compared to 32% of controls (P < 0.01). Morbidly obese patients had a longer first stage of labor (P < 0.01), larger neonates (P < 0.01), and were more likely to have a failed initial neuraxial technique for labor analgesia (P < 0.01). The need for a replacement procedure for labor was 17%, significantly less than 20 years ago when 42% of catheters in morbidly obese women failed (P < 0.01). Failure rates of neuraxial anesthesia for cesarean delivery were similar between groups. Neuraxial procedure times were greater in morbidly obese parturients (P < 0.01). Morbidly obese women were less likely to receive general anesthesia compared to 20 years ago (3% vs. 24%, P < 0.01).
Morbidly obese parturients are still at increased risk for antenatal comorbidities, failed labor analgesia, longer first stage of labor and operative delivery. Replacement labor epidural catheters and general anesthesia for cesarean delivery are less commonly required anesthetic techniques compared to the original study.
1993年,胡德和德万公布了一项试验结果,该试验比较了117例病态肥胖产妇与匹配对照组的产科和麻醉结局。作者证明了初始硬膜外麻醉失败率更高、剖宫产率更高以及产科并发症风险增加。我们重复了先前的研究,以提供病态肥胖孕妇结局的最新信息。我们假设,与匹配对照组相比,病态肥胖女性的并发症和失败率仍然更高,并且全身麻醉的使用频率将低于先前的研究。
将230例体重>136千克(300磅)患者的病历与匹配对照组进行比较:由同一位产科医生接生的下一位体重<113千克(250磅)的患者。
病态肥胖组的平均体重指数为53.4±6.6千克/平方米[校正后],而对照组为31.1±5.4千克/平方米。50%的病态肥胖女性需要剖宫产,而对照组为32%(P<0.01)。病态肥胖患者的第一产程更长(P<0.01),新生儿更大(P<0.01),并且更有可能在初始分娩镇痛时出现椎管内技术失败(P<0.01)。分娩时需要更换程序的比例为17%,显著低于20年前,当时病态肥胖女性中有42%的导管失败(P<0.01)。剖宫产椎管内麻醉的失败率在两组之间相似。病态肥胖产妇的椎管内操作时间更长(P<0.01)。与20年前相比,病态肥胖女性接受全身麻醉的可能性更小(3%对24%,P<0.01)。
病态肥胖产妇在产前合并症、分娩镇痛失败、第一产程延长和手术分娩方面的风险仍然增加。与原始研究相比,更换分娩硬膜外导管和剖宫产全身麻醉的麻醉技术需求较少。