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肥胖产妇硬膜外镇痛:与一家三级医院非肥胖产妇的回顾性和对比研究。

Epidural analgesia in the obese obstetric patient: a retrospective and comparative study with non-obese patients at a tertiary hospital.

机构信息

Servicio de Anestesiología y Reanimación, Hospital universitario La Paz, Madrid, Spain.

Servicio de Anestesiología y Reanimación, Hospital universitario La Paz, Madrid, Spain.

出版信息

Braz J Anesthesiol. 2021 May-Jun;71(3):214-220. doi: 10.1016/j.bjane.2021.02.054. Epub 2021 Apr 9.

DOI:10.1016/j.bjane.2021.02.054
PMID:33845099
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9373670/
Abstract

BACKGROUND AND OBJECTIVES

Obesity is becoming a frequent condition among obstetric patients. A high body mass index (BMI) has been closely related to a higher difficulty to perform the neuraxial technique and to the failure of epidural analgesia. Our study is aimed at analyzing obese obstetric patients who received neuraxial analgesia for labor at a tertiary hospital and assessing aspects related to the technique and its success.

METHODS

Retrospective observational descriptive study during one year. Women with a BMI higher than 30 were identified, and variables related to the difficulty and complications of performing the technique, and to analgesia failure rate were assessed.

RESULTS AND CONCLUSIONS

Out of 3653 patients, 27.4% had their BMI ≥ 30 kg.m-². Neuraxial techniques are difficult to be performed in obese obstetric patients, as showed by the number of puncture attempts (≥ 3 in 9.1% obese versus 5.3% in non-obese being p < 0.001), but the incidence of complications, as hematic puncture (6.6%) and accidental dural puncture (0.7%) seems to be similar in both obese and non-obese patients. The incidence of cesarean section in obese patients was 23.4% (p <  0.001). Thus, an early performance of epidural analgesia turns out to be essential to control labor pain and to avoid a general anesthesia in such high-risk patients.

摘要

背景和目的

肥胖症在产科患者中越来越常见。高体重指数(BMI)与进行神经轴突技术的难度增加以及硬膜外镇痛失败密切相关。我们的研究旨在分析在一家三级医院接受分娩神经轴突镇痛的肥胖产科患者,并评估与技术及其成功率相关的方面。

方法

在一年期间进行回顾性观察描述性研究。确定 BMI 高于 30 的女性,并评估与技术难度和并发症以及镇痛失败率相关的变量。

结果和结论

在 3653 名患者中,27.4%的患者 BMI≥30kg.m-²。肥胖产科患者的神经轴突技术难以实施,表现为穿刺尝试次数(≥3 次,肥胖患者为 9.1%,非肥胖患者为 5.3%,p<0.001),但出血性穿刺(6.6%)和意外硬脊膜穿刺(0.7%)等并发症的发生率在肥胖和非肥胖患者中似乎相似。肥胖患者的剖宫产率为 23.4%(p<0.001)。因此,早期进行硬膜外镇痛对于控制分娩疼痛和避免此类高风险患者的全身麻醉至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff6/9373670/74afbfd80aff/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff6/9373670/74afbfd80aff/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff6/9373670/74afbfd80aff/gr1.jpg

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本文引用的文献

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Obesity And Obstetric Anesthesia: Current Insights.肥胖与产科麻醉:当前见解
Local Reg Anesth. 2019 Nov 18;12:111-124. doi: 10.2147/LRA.S186530. eCollection 2019.
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Does maternal obesity explain trends in caesarean section rates? Evidence from a large Irish maternity hospital.产妇肥胖是否可以解释剖宫产率的变化趋势?来自爱尔兰一家大型妇产医院的证据。
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Maternal and perinatal outcomes in pregnant women with BMI >50: An international collaborative study.
超重孕妇(BMI>50)的母婴围产结局:一项国际合作研究。
PLoS One. 2019 Feb 4;14(2):e0211278. doi: 10.1371/journal.pone.0211278. eCollection 2019.
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Increasing body mass index and abdominal subcutaneous fat thickness are associated with increased skin-to-epidural space distance in pregnant women.孕妇的体重指数和腹部皮下脂肪厚度增加与皮肤到硬膜外腔的距离增加有关。
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Anesthetic and obstetric outcomes in pregnant women undergoing cesarean delivery according to body mass index: Retrospective analysis of a single-center experience.根据体重指数对剖宫产孕妇的麻醉和产科结局:单中心经验的回顾性分析
Ann Med Surg (Lond). 2018 Nov 2;36:129-134. doi: 10.1016/j.amsu.2018.10.023. eCollection 2018 Dec.
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Ultrasound-Assisted Technology Versus the Conventional Landmark Location Method in Spinal Anesthesia for Cesarean Delivery in Obese Parturients: A Randomized Controlled Trial.超声辅助技术与传统地标定位法在肥胖产妇剖宫产椎管内麻醉中的比较:一项随机对照试验。
Anesth Analg. 2019 Jul;129(1):155-161. doi: 10.1213/ANE.0000000000003795.
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Risk assessment of morbidly obese parturient in cesarean section delivery: A prospective, cohort, single-center study.剖宫产术中病态肥胖产妇的风险评估:一项前瞻性队列单中心研究。
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