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在辅助生殖技术前使用爱适孕(Essure®)对输卵管积水进行近端封堵:一项法国调查。

Proximal occlusion of hydrosalpinges by Essure(®) before assisted reproduction techniques: a French survey.

作者信息

Legendre Guillaume, Moulin Julie, Vialard Jean, Ziegler Dominique D E, Fanchin Renato, Pouly Jean Luc, Watrelot Antoine, Belaisch Allart Joëlle, Massin Nathalie, Fernandez Hervé

机构信息

Service de Gynécologie-Obstétrique, Assistance publique des hôpitaux de Paris- Hôpital de Bicêtre, Le Kremlin-Bicêtre, France.

Service de Gynécologie-Obstétrique, Clinique mutualiste La Sagesse, Rennes, France.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2014 Oct;181:300-4. doi: 10.1016/j.ejogrb.2014.07.020. Epub 2014 Jul 30.

DOI:10.1016/j.ejogrb.2014.07.020
PMID:25201610
Abstract

OBJECTIVES

To study the feasibility and results (live-birth and complication rates) of placement of Essure(®) microinserts before assisted reproductive technology (ART) treatment of women with hydrosalpinx when laparoscopy should be avoided. Study design National survey of 45 French hospital centres providing ART reporting a retrospective analysis of 43 women with unilateral or bilateral hydrosalpinges and Essure(®) placement. The results of the following ART cycle were studied for 54 embryo transfers.

RESULTS

The placement success rate reached 92.8% (65/70 tubes), and the mean number of visible intrauterine coils was 1.61 (range: 0-6). Pyosalpinx occurred in one case, and expulsion of the device into the uterus in two others. Of 43 women, 29 (67.4%) had a total of 54 fresh or frozen embryos transferred. The clinical pregnancy rate was 40.7% (22/54) and the live-birth rate 25.9% (14/54). The implantation rate was 29.3% (27/92).

CONCLUSION

Essure(®) placement is an effective method for occlusion of hydrosalpinges before IVF. Monitoring the live-birth rate confirms that this option is the strongest in cases when laparoscopy is impossible or contraindicated.

摘要

目的

研究在应避免腹腔镜检查的输卵管积水女性辅助生殖技术(ART)治疗前放置Essure(®)微插入物的可行性及结果(活产率和并发症发生率)。研究设计 对45家提供ART的法国医院中心进行全国性调查,报告对43例单侧或双侧输卵管积水并放置Essure(®)的女性进行回顾性分析。对54次胚胎移植的以下ART周期结果进行研究。

结果

放置成功率达到92.8%(65/70条输卵管),子宫内可见线圈的平均数量为1.61(范围:0 - 6)。1例发生输卵管积脓,另2例装置排入子宫。43例女性中,29例(67.4%)共进行了54次新鲜或冷冻胚胎移植。临床妊娠率为40.7%(22/54),活产率为25.9%(14/54)。着床率为29.3%(27/92)。

结论

放置Essure(®)是IVF前阻塞输卵管积水的有效方法。监测活产率证实,在不可能或禁忌进行腹腔镜检查的情况下,该选择是最佳的。

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