Heller Rebecca, Cameron Sharon
Clinical Research Fellow, Chalmers Sexual & Reproductive Health Service, Edinburgh, UK.
Consultant Gynaecologist, Chalmers Sexual & Reproductive Health Service, Edinburgh, UK.
J Fam Plann Reprod Health Care. 2015 Apr;41(2):90-5. doi: 10.1136/jfprhc-2014-100924. Epub 2014 Sep 8.
Requests for termination of pregnancy (TOP) at very early gestation (≤6 weeks) can prove challenging for abortion services as the ultrasound feature usually accepted as definitive evidence of an intrauterine pregnancy (IUP), the presence of a yolk sac within a gestational sac, may not yet be evident. In 2011 the Edinburgh TOP service introduced a protocol permitting women to proceed to treatment without further investigations provided that ultrasound showed the features of an eccentrically placed gestational sac (≥3 mm) with a decidual reaction, and there were no signs, symptoms or risk factors for ectopic pregnancy.
A retrospective audit was conducted of outcomes of women presenting for TOP at ≤6 weeks' gestation over a 2-year period using the hospital computerised database.
A total of 1155 women presented for TOP with an ultrasound gestational age of ≤6 weeks. Of these, 1030 (89%) had ultrasound evidence of a yolk sac. Eighty-seven women (7.5%) had an eccentrically placed gestational sac with a decidual reaction. All 87 women fulfilled our criteria to proceed to medical TOP, and 66 did so. In the remaining 21 cases, further investigations were performed before they proceeded to medical TOP. Two (0.17%) medical TOPs failed, both in women whose initial ultrasound had shown a yolk sac.
Women with ultrasound features consistent with a very early IUP (≥3 mm eccentrically placed gestational sac with a decidual reaction) and without signs, symptoms or risk factors for ectopic pregnancy can proceed directly to medical TOP without the need for delay for further ultrasonography.
对于早期妊娠(≤6周)终止妊娠(TOP)的请求,流产服务可能颇具挑战,因为通常被视为宫内妊娠(IUP)确凿证据的超声特征,即妊娠囊内卵黄囊的存在,可能尚不明显。2011年,爱丁堡TOP服务引入了一项方案,允许女性在超声显示妊娠囊偏心放置(≥3毫米)且有蜕膜反应、无异位妊娠体征、症状或风险因素的情况下,无需进一步检查即可进行治疗。
利用医院计算机数据库,对2年期间妊娠≤6周前来进行TOP的女性的结局进行回顾性审计。
共有1155名妊娠≤6周的女性前来进行TOP。其中,1030名(89%)有超声显示卵黄囊的证据。87名女性(7.5%)有偏心放置且有蜕膜反应的妊娠囊。所有87名女性均符合我们进行药物性TOP的标准,其中66名进行了药物性TOP。在其余21例中,在进行药物性TOP之前进行了进一步检查。2例(0.17%)药物性TOP失败,均为最初超声显示有卵黄囊的女性。
超声特征符合极早期IUP(偏心放置≥3毫米且有蜕膜反应的妊娠囊)且无异位妊娠体征、症状或风险因素的女性,可直接进行药物性TOP,无需延迟进行进一步超声检查。