The Medical School, University of Edinburgh, Edinburgh, UK.
Queen's Medical Research Institute, MRC Centre for Reproductive Health, University of Edinburgh, Edinburgh, UK.
BMJ Sex Reprod Health. 2022 Jan;48(1):22-27. doi: 10.1136/bmjsrh-2020-200888. Epub 2020 Dec 29.
Routine ultrasound may be used in abortion services to determine gestational age and confirm an intrauterine pregnancy. However, ultrasound adds complexity to care and results may be inconclusive, delaying abortion. We sought to determine the rate of ectopic pregnancy and the utility of routine ultrasound in its detection, in a community abortion service.
Retrospective case record review of women requesting abortion over a 5-year period (2015-2019) with an outcome of ectopic pregnancy or pregnancy of unknown location (PUL) at a service (Edinburgh, UK) conducting routine ultrasound on all women. Records were searched for symptoms at presentation, development of symptoms during clinical care, significant risk factors and routine ultrasound findings.
Only 29/11 381 women (0.25%, 95% CI 0.18%, 0.33%) had an ectopic pregnancy or PUL (tubal=18, caesarean scar=1, heterotopic=1, PUL=9). Eleven (38%) cases had either symptoms at presentation (n=8) and/or significant risk factors for ectopic pregnancy (n=4). A further 12 women developed symptoms during their clinical care. Of the remaining six, three were PUL treated with methotrexate and three were ectopic (salpingectomy=2, methotrexate=1). In three cases, the baseline ultrasound indicated a probable early intrauterine pregnancy.
Ectopic pregnancies are uncommon among women presenting for abortion. The value of routine ultrasound in excluding ectopic pregnancy in symptom-free women without significant risk factors is questionable as it may aid detection of some cases but may provide false reassurance that a pregnancy is intrauterine.
常规超声检查可用于流产服务,以确定妊娠龄并确认宫内妊娠。然而,超声检查增加了护理的复杂性,且结果可能不确定,从而导致流产延迟。我们旨在确定在一个社区流产服务中,异位妊娠的发生率以及常规超声检查在其检测中的作用。
对在五年期间(2015-2019 年)在一家服务机构(英国爱丁堡)要求流产且结局为异位妊娠或妊娠位置不明(PUL)的妇女进行回顾性病例记录回顾。该服务机构对所有妇女均进行常规超声检查。对就诊时的症状、临床护理期间症状的发展、显著的危险因素和常规超声检查结果进行记录检索。
仅 29/11381 名妇女(0.25%,95%CI 0.18%,0.33%)患有异位妊娠或 PUL(输卵管妊娠 18 例、剖宫产瘢痕妊娠 1 例、异位妊娠 1 例、PUL 9 例)。11 例(38%)病例就诊时出现症状(n=8)和/或存在异位妊娠的显著危险因素(n=4)。另有 12 例妇女在临床护理期间出现症状。其余 6 例中,3 例 PUL 采用甲氨蝶呤治疗,3 例为异位妊娠(输卵管切除术 2 例,甲氨蝶呤 1 例)。在 3 例中,基线超声检查提示可能为早期宫内妊娠。
在进行流产的妇女中,异位妊娠并不常见。对于无症状且无显著危险因素的妇女,常规超声检查在排除异位妊娠方面的价值值得怀疑,因为它可能有助于发现一些病例,但可能会错误地认为妊娠是宫内的。