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心脏原发性骨肉瘤伴长期生存:腹腔镜切除肠道转移性肉瘤的病例报告

Primary osteosarcoma of the heart with long-term survival: A case report of laparoscopic resection of a metastatic sarcoma in the intestine.

作者信息

Fujino Shiki, Miyoshi Norikatsu, Ohue Masayuki, Noura Shingo, Hamamoto Shuichi, Oshima Kazuya, Araki Nobuhito, Tomita Yasuhiko, Yano Masahiko

机构信息

Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Higashinari-ku, Osaka 537-8511, Japan.

Department of Orthopedic Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Higashinari-ku, Osaka 537-8511, Japan.

出版信息

Oncol Lett. 2014 Oct;8(4):1599-1602. doi: 10.3892/ol.2014.2405. Epub 2014 Aug 1.

Abstract

Primary cardiac tumors are uncommon and cardiac osteosarcoma is a rare disease. While complete surgical resection is considered to be the best treatment option for cardiac osteosarcomas, local and metastatic recurrences present challenges and indicate a poor prognosis. A combination of surgical resection with radio- and/or chemotherapy is a more effective course of treatment for osteosarcoma. In the present case, the patient underwent a complete resection of a primary cardiac osteosarcoma, and received chemotherapy and radiotherapy following local recurrence and metastasis to the bone post-operatively. Following these treatments, a rectal metastatic tumor was detected as causative of anemia. There is currently a lack of guidelines on the treatment of metastatic osteosarcomas in the intestine and there are few reports on rectal metastases. The present study described a laparoscopic resection of the osteosarcoma. The patient recovered without any complications and radiotherapy and chemotherapy were administered post-surgery to treat the bone metastases. The patient remained healthy at a follow-up examination, 61 months post surgery.

摘要

原发性心脏肿瘤并不常见,心脏骨肉瘤是一种罕见疾病。虽然完整的手术切除被认为是心脏骨肉瘤的最佳治疗选择,但局部和转移性复发带来了挑战,且提示预后不良。手术切除联合放疗和/或化疗是骨肉瘤更有效的治疗方案。在本病例中,患者接受了原发性心脏骨肉瘤的完整切除,并在术后局部复发和骨转移后接受了化疗和放疗。经过这些治疗后,检测到直肠转移性肿瘤是贫血的病因。目前缺乏关于肠道转移性骨肉瘤治疗的指南,关于直肠转移的报道也很少。本研究描述了骨肉瘤的腹腔镜切除。患者康复且无任何并发症,术后给予放疗和化疗以治疗骨转移。在术后61个月的随访检查中,患者保持健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43e4/4156191/5c2cb6d00ce7/OL-08-04-1599-g00.jpg

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