Fujino Shiki, Miyoshi Norikatsu, Ohue Masayuki, Noura Shingo, Hamamoto Shuichi, Oshima Kazuya, Araki Nobuhito, Tomita Yasuhiko, Yano Masahiko
Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Higashinari-ku, Osaka 537-8511, Japan.
Department of Orthopedic Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Higashinari-ku, Osaka 537-8511, Japan.
Oncol Lett. 2014 Oct;8(4):1599-1602. doi: 10.3892/ol.2014.2405. Epub 2014 Aug 1.
Primary cardiac tumors are uncommon and cardiac osteosarcoma is a rare disease. While complete surgical resection is considered to be the best treatment option for cardiac osteosarcomas, local and metastatic recurrences present challenges and indicate a poor prognosis. A combination of surgical resection with radio- and/or chemotherapy is a more effective course of treatment for osteosarcoma. In the present case, the patient underwent a complete resection of a primary cardiac osteosarcoma, and received chemotherapy and radiotherapy following local recurrence and metastasis to the bone post-operatively. Following these treatments, a rectal metastatic tumor was detected as causative of anemia. There is currently a lack of guidelines on the treatment of metastatic osteosarcomas in the intestine and there are few reports on rectal metastases. The present study described a laparoscopic resection of the osteosarcoma. The patient recovered without any complications and radiotherapy and chemotherapy were administered post-surgery to treat the bone metastases. The patient remained healthy at a follow-up examination, 61 months post surgery.
原发性心脏肿瘤并不常见,心脏骨肉瘤是一种罕见疾病。虽然完整的手术切除被认为是心脏骨肉瘤的最佳治疗选择,但局部和转移性复发带来了挑战,且提示预后不良。手术切除联合放疗和/或化疗是骨肉瘤更有效的治疗方案。在本病例中,患者接受了原发性心脏骨肉瘤的完整切除,并在术后局部复发和骨转移后接受了化疗和放疗。经过这些治疗后,检测到直肠转移性肿瘤是贫血的病因。目前缺乏关于肠道转移性骨肉瘤治疗的指南,关于直肠转移的报道也很少。本研究描述了骨肉瘤的腹腔镜切除。患者康复且无任何并发症,术后给予放疗和化疗以治疗骨转移。在术后61个月的随访检查中,患者保持健康。