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肥胖是否会影响退行性脊柱侧凸的手术效果?

Does obesity affect surgical outcomes in degenerative scoliosis?

作者信息

Fu Lingjie, Chang Michael S, Crandall Dennis G, Revella Jan

机构信息

*Department of Orthopaedic Surgery, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P. R. China †Sonoran Spine Center, Phoenix, AZ ‡Sonoran Spine Research and Education Foundation, Phoenix, AZ §Banner Good Samaritan Orthopedic Surgery Residency Program, Phoenix, AZ; and ¶Department of Orthopaedic Surgery, University of Arizona, Phoenix, AZ.

出版信息

Spine (Phila Pa 1976). 2014 Nov 15;39(24):2049-55. doi: 10.1097/BRS.0000000000000600.

Abstract

STUDY DESIGN

Retrospective cohort analysis of prospectively collected data.

OBJECTIVE

To determine whether an association exists between body mass and surgical outcomes in patients with degenerative scoliosis after long instrumented spinal arthrodesis (≥ 4 discs).

SUMMARY OF BACKGROUND DATA

Obesity is thought to be associated with increased surgical complications and inferior clinical outcomes in adults. There are no studies analyzing the effect of obesity on surgical outcomes in patients with degenerative scoliosis after long instrumented spinal arthrodesis.

METHODS

Eighty-four consecutive patients with degenerative scoliosis (69 females and 15 males; mean age, 68.6 ± 8.0 yr) with a minimum follow-up of 2 years were included in this study. Patients were divided into 3 groups according to body mass index (BMI): obese (BMI ≥ 30 kg/m², n = 19), overweight (BMI = 25-29.9 kg/m², n = 35), and normal weight (BMI < 25 kg/m², n = 30). Radiographical measures, Oswestry Disability Index, visual analogue scale score, as well as comorbidities and complications were reviewed and analyzed for all patients preoperatively and at 1- and 2-year follow-ups.

RESULTS

Compared with the normal weight group, no significant differences in surgical methods, comorbidities, complication rates, curve correction, or radiographical measures were found in the obese and overweight groups, except for a greater preoperative lumbar lordosis in the overweight group (-40.3° ± 13.8° vs. -26.0° ± 18.9°, P < 0.05). At 2-year follow-up, Oswestry Disability Index and visual analogue scalescores improved significantly in all groups compared with preoperatively (P < 0.01). The changes of Oswestry Disability Index and visual analogue scalescores from preoperatively to final follow-up were similar in the 3 groups (P > 0.05).

CONCLUSION

Obesity did not affect the amount of deformity correction and did not increase comorbidities and postoperative complication rates. Overweight patients had a greater lumbar lordosis before surgery than normal weight patients. Obese and overweight patients benefited from surgery just as much as normal weight patients at 2-year follow-up.

摘要

研究设计

对前瞻性收集的数据进行回顾性队列分析。

目的

确定退行性脊柱侧弯患者在长节段器械辅助脊柱融合术(≥4个椎间盘)后,体重与手术结果之间是否存在关联。

背景数据总结

肥胖被认为与成人手术并发症增加及临床结果较差有关。尚无研究分析肥胖对长节段器械辅助脊柱融合术后退行性脊柱侧弯患者手术结果的影响。

方法

本研究纳入了84例连续的退行性脊柱侧弯患者(69例女性和15例男性;平均年龄68.6±8.0岁),最小随访时间为2年。根据体重指数(BMI)将患者分为3组:肥胖组(BMI≥30kg/m²,n = 19)、超重组(BMI = 25 - 29.9kg/m²,n = 35)和正常体重组(BMI < 25kg/m²,n = 30)。对所有患者术前以及1年和2年随访时的影像学测量、Oswestry功能障碍指数、视觉模拟量表评分以及合并症和并发症进行回顾和分析。

结果

与正常体重组相比,肥胖组和超重组在手术方式、合并症、并发症发生率、侧弯矫正或影像学测量方面均无显著差异,但超重组术前腰椎前凸更大(-40.3°±13.8°对-26.0°±18.9°,P < 0.05)。在2年随访时,与术前相比,所有组的Oswestry功能障碍指数和视觉模拟量表评分均显著改善(P < 0.01)。3组从术前到最终随访时Oswestry功能障碍指数和视觉模拟量表评分的变化相似(P > 0.05)。

结论

肥胖不影响畸形矫正量,也不会增加合并症和术后并发症发生率。超重患者术前腰椎前凸比正常体重患者更大。在2年随访时,肥胖和超重患者与正常体重患者从手术中获益程度相同。

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