难治性三叉神经痛的新型治疗方法。

Novel treatment in refractory tic douloureux.

作者信息

Soleimanpour Hassan, Aghamohammadi Dawood, Ghaffarzad Amir, Golzari Samad Ej, Safari Saeid, Soleimanpour Maryam

机构信息

Cardiovascular Research Center, Tabriz University of Medical Sciences, Daneshgah St., Tabriz-51664, I.R., Iran.

Department of Anesthesiology and Critical Care, Tabriz University of Medical Sciences, Daneshgah St., Tabriz-51664, I.R., Iran.

出版信息

J Clin Anesth. 2014 Sep;26(6):495-6. doi: 10.1016/j.jclinane.2014.03.011. Epub 2014 Sep 7.

DOI:10.1016/j.jclinane.2014.03.011

PMID:25204512

Abstract

A patient with refractory trigeminal neuralgia (tic douloureux) was treated by intravenous magnesium sulfate successfully. Parenteral magnesium sulfate is an analgesic that expresses its analgesic effects through a noncompetitive blockade of the N-methyl-D-aspartate (NMDA) receptors, which in turns inhibits calcium entry into the cells.

摘要

一名难治性三叉神经痛（痛性抽搐）患者通过静脉注射硫酸镁成功治愈。胃肠外使用的硫酸镁是一种镇痛药，它通过非竞争性阻断N-甲基-D-天冬氨酸（NMDA）受体发挥镇痛作用，进而抑制钙进入细胞。