IgG4相关性疾病在咽部的临床表现：病例系列及文献综述
Clinical Manifestations of IgG4-Related Disease in the Pharynx: Case Series and Review of the Literature.
作者信息
Reder Lindsay, Della-Torre Emanuel, Stone John H, Mori Matthew, Song Phillip
机构信息
Department of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, California, USA.
Università Vita-Salute San Raffaele, Unit of Medicine and Clinical Immunology, San Raffaele Scientific Institute, Milan, Italy Harvard Medical School, Boston, Massachusetts, USA.
出版信息
Ann Otol Rhinol Laryngol. 2015 Mar;124(3):173-8. doi: 10.1177/0003489414549574. Epub 2014 Sep 9.
OBJECTIVE
The objective of this report is to characterize IgG4-related disease (IgG4-RD) as it is manifested in the head and neck and describe a series of patients with a rarely described presentation in laryngopharyngeal subsites.
METHODS
Here, we illustrate the presentation and clinical course of 3 patients with laryngopharyngeal manifestations of IgG4-RD, including the manner of diagnosis and effective treatment.
RESULTS
Three patients with laryngopharyngeal lesions were ultimately diagnosed with IgG4-RD after lengthy work-up. The diagnostic criteria and treatment protocols are explained.
CONCLUSION
IgG4-related disease is a fibroinflammatory disorder now described in almost every organ system. The head and neck regions are among the most common areas of involvement, however, reports of laryngopharyngeal involvement are rare. We also summarize current knowledge of this entity and discuss established diagnostic criteria and clinical findings.
目的
本报告的目的是描述头颈部表现出的IgG4相关性疾病（IgG4-RD），并描述一系列在喉咽亚部位有罕见表现的患者。
方法
在此，我们阐述了3例有IgG4-RD喉咽表现患者的临床表现及病程，包括诊断方式和有效治疗方法。
结果
3例有喉咽病变的患者经过长时间检查最终被诊断为IgG4-RD。文中解释了诊断标准和治疗方案。
结论
IgG4相关性疾病是一种现在几乎在每个器官系统中都有描述的纤维炎性疾病。头颈部是最常受累的区域之一，然而，关于喉咽受累的报道很少。我们还总结了该疾病的现有知识，并讨论了既定的诊断标准和临床发现。
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