Department of Biomedical Engineering, Wayne State University, Detroit, MI, USA ; Department of Radiology, Wayne State University, Detroit, MI, USA.
Department of Biomedical Engineering, Wayne State University, Detroit, MI, USA.
Neural Regen Res. 2014 Apr 1;9(7):693-700. doi: 10.4103/1673-5374.131568.
The brain is highly plastic after stroke or epilepsy; however, there is a paucity of brain plasticity investigation after traumatic brain injury (TBI). This mini review summarizes the most recent evidence of brain plasticity in human TBI patients from the perspective of advanced magnetic resonance imaging. Similar to other forms of acquired brain injury, TBI patients also demonstrated both structural reorganization as well as functional compensation by the recruitment of other brain regions. However, the large scale brain network alterations after TBI are still unknown, and the field is still short of proper means on how to guide the choice of TBI rehabilitation or treatment plan to promote brain plasticity. The authors also point out the new direction of brain plasticity investigation.
大脑在中风或癫痫后具有高度的可塑性;然而,在创伤性脑损伤(TBI)后,对大脑可塑性的研究却很少。本综述从高级磁共振成像的角度总结了人类 TBI 患者大脑可塑性的最新证据。与其他形式的获得性脑损伤类似,TBI 患者还通过招募其他脑区来实现结构重组和功能代偿。然而,TBI 后大规模的脑网络改变仍不清楚,该领域还缺乏适当的方法来指导 TBI 康复或治疗计划的选择,以促进大脑的可塑性。作者还指出了大脑可塑性研究的新方向。