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格叶榕毒素(醉果)中毒后的持续摄入。

Grayanotoxin (mad honey) - ongoing consumption after poisoning.

机构信息

Department of Emergency Medicine, Marmara University Pendik Research and Training Hospital, İstanbul, Turkey.

出版信息

Balkan Med J. 2013 Sep;30(3):293-5. doi: 10.5152/balkanmedj.2013.8100. Epub 2013 Sep 1.

Abstract

BACKGROUND

Some honey types in certain geographical regions may cause toxic effects on people. This type of honey is known as "mad honey" in Turkey. The toxic ingredient of this honey is called Grayanotoxin I. The consumption of mad honey can cause severe bradycardia, hypotension, dizziness, nausea and vomiting.

AIMS

Our study is aimed at analysing patients diagnosed with mad honey poisoning and their behaviour towards the consumption of this honey after diagnosis.

STUDY DESIGN

Cross sectional study.

METHODS

This cross-sectional study was based on complaints and findings of mad honey poisoning. Patient information and findings at the time of admission were compared with those at one month after discharge through telephone interviews. They were asked if either they or their relatives had continued consuming the same honey. Frequency data such as gender, purpose of honey consumption, first complaints and continuance of honey consumption are shown as number (n) and percentage (%). A Chi Square test was conducted to determine the difference between groups.

RESULTS

38 patients were participated in this study; 18 of the patients had to be followed up in a coronary intensive care unit. We were able to reach 34 patients by phone after discharge. It was found that 12 of 16 patients discharged after emergency unit observation or their close relatives were continuing to consume mad honey, whereas 16 (88.9%) of the 18 patients under coronary intensive care had discontinued consuming mad honey. The difference in the continuation of mad honey consumption between patient groups followed-up in the intensive care unit and those discharged after emergency observation was statistically significant.

CONCLUSION

Hazards associated with and serious consequences following the consumption of mad honey must be clearly explained to patients who are found to be consuming mad honey.

摘要

背景

某些地理区域的某些蜂蜜类型可能会对人体造成毒性作用。这种蜂蜜在土耳其被称为“疯蜜”。这种蜂蜜的有毒成分称为格尼帕毒素 I。食用疯蜜会导致严重的心动过缓、低血压、头晕、恶心和呕吐。

目的

我们的研究旨在分析诊断为疯蜜中毒的患者及其在诊断后对食用这种蜂蜜的行为。

研究设计

横断面研究。

方法

这项横断面研究基于疯蜜中毒的投诉和发现。通过电话访谈,将患者入院时的信息和发现与出院后一个月的信息和发现进行比较。询问他们或他们的亲属是否继续食用同一种蜂蜜。性别、食用蜂蜜的目的、首次投诉和继续食用蜂蜜等频率数据以数字(n)和百分比(%)表示。进行卡方检验以确定组间差异。

结果

共有 38 名患者参与了这项研究,其中 18 名患者必须在冠心病重症监护病房接受随访。出院后,我们通过电话联系到了 34 名患者。结果发现,16 名在急诊观察后出院的患者或其亲属中有 12 人继续食用疯蜜,而 18 名在冠心病重症监护病房的患者中有 16 人(88.9%)停止食用疯蜜。在重症监护病房和急诊观察后出院的患者组之间继续食用疯蜜的差异具有统计学意义。

结论

必须向发现食用疯蜜的患者清楚地解释食用疯蜜相关的危害和严重后果。

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本文引用的文献

1
Mad honey sex: therapeutic misadventures from an ancient biological weapon.
Ann Emerg Med. 2009 Dec;54(6):824-9. doi: 10.1016/j.annemergmed.2009.06.010. Epub 2009 Aug 15.
2
Does mad honey poisoning require hospital admission?
Am J Emerg Med. 2009 May;27(4):424-7. doi: 10.1016/j.ajem.2008.03.021.
4
Mad honey poisoning-related asystole.
Emerg Med J. 2007 Aug;24(8):592-3. doi: 10.1136/emj.2006.045625.
5
Mad honey poisoning.
Am J Emerg Med. 2006 Sep;24(5):595-8. doi: 10.1016/j.ajem.2006.01.022.
6
Hypotension, bradycardia and syncope caused by honey poisoning.
Resuscitation. 2006 Mar;68(3):405-8. doi: 10.1016/j.resuscitation.2005.07.014. Epub 2006 Feb 2.
7
Cardiac emergencies caused by honey ingestion: a single centre experience.
Emerg Med J. 2004 Nov;21(6):742-4. doi: 10.1136/emj.2003.009324.
8
Poisoning by toxic honey in Turkey.
Arch Toxicol. 1993;67(2):148-50. doi: 10.1007/BF01973687.
9
[Poisoning with andromedotoxin-containing honey].
Dtsch Med Wochenschr. 1983 Oct 14;108(41):1555-8. doi: 10.1055/s-2008-1069784.
10
Mad honey poisoning in man and rat.
Rev Environ Health. 1991;9(1):3-9. doi: 10.1515/reveh.1991.9.1.3.

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