比伐卢定在植入全人工心脏过程中用于抗凝。
Use of bivalirudin for anticoagulation during implantation of total artificial heart.
作者信息
Federman Myke, Dragomer Douglas, Grant Stuart, Reemtsen Brian, Biniwale Reshma
出版信息
J Extra Corpor Technol. 2014 Jun;46(2):170-2.
Abstract
Heparin-induced thrombocytopenia presents a challenge for anticoagulation techniques during cardiac surgery and ventricular assist device implantation. Bivalirudin is currently recommended for use during cardiopulmonary bypass for patients with heparin-induced thrombocytopenia but requires the use of special techniques to avoid blood stagnation. We report the successful use of bivalirudin during cardiopulmonary bypass for implantation of the Total Artificial Heart with late operative bleeding likely resulting from heavy cell saver use.
摘要
肝素诱导的血小板减少症给心脏手术和心室辅助装置植入期间的抗凝技术带来了挑战。目前推荐在体外循环期间，对患有肝素诱导的血小板减少症的患者使用比伐卢定，但需要采用特殊技术以避免血液淤滞。我们报告了在体外循环期间成功使用比伐卢定植入全人工心脏的案例，术后晚期出血可能是由于大量使用细胞回收器所致。
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