Dragomer D, Chalfant A, Biniwale R, Reemtsen B, Federman M
Perfusion Services, University of California, Los Angeles, CA, USA.
Perfusion. 2011 Nov;26(6):516-8. doi: 10.1177/0267659111419037. Epub 2011 Aug 9.
Heparin-induced thrombocytopenia (HIT) occurs in both the pediatric and adult populations after exposure to heparin. Bivalirudin has been used as an alternative to heparin for adults undergoing cardiac surgery and cardiopulmonary bypass, but has only been used minimally in children for this purpose. We report the successful use of bivalirudin for anticoagulation during cardiopulmonary bypass in a small child with HIT, using novel techniques not previously described.
肝素诱导的血小板减少症（HIT）在儿童和成人接触肝素后均会发生。比伐卢定已被用作接受心脏手术和体外循环的成人患者替代肝素的药物，但在儿童中仅极少用于此目的。我们报告了在一名患有HIT的小儿体外循环期间成功使用比伐卢定进行抗凝的情况，采用了此前未描述的新技术。
