Eisermann J, Yang V, Register K, Swank N, Strickler R C
Department of Obstetrics and Gynecology, Jewish Hospital, Washington University Medical Center, St. Louis, Missouri 63110.
Fertil Steril. 1989 Jan;51(1):112-6. doi: 10.1016/s0015-0282(16)60438-7.
The effect of a combined pure follicle-stimulating hormone/human menopausal gonadotropin (pFSH/hMG) ovarian stimulation regimen and modified, sharpened laparoscopic follicular aspiration needles on the number of oocytes retrieved and the oocyte/follicle ratio in 43 consecutive cycles of in vitro fertilization (IVF) were retrospectively compared with 99 consecutive preceeding cycles stimulated with hMG alone and captured with aspiration needles that had never been sharpened. A modified laparoscopic follicular aspiration needle is described. Purified FSH/hMG ovarian stimulation significantly improved the mean serum estradiol levels, number of preovulatory follicles, and, therefore, the total number of oocytes recovered per cycle. The mean ratios of oocytes recovered per preovulatory follicle documented on ultrasound, and per aspirated follicle, increased significantly using sharpened needles. Both modifications improved the success rate of our IVF program.
将43个连续的体外受精（IVF）周期中，联合使用纯卵泡刺激素/人绝经期促性腺激素（pFSH/hMG）进行卵巢刺激方案以及改良的、尖锐的腹腔镜卵泡抽吸针，与之前99个仅用hMG刺激且使用从未磨尖过的抽吸针采集的连续周期进行回顾性比较，观察其对回收的卵母细胞数量和卵母细胞/卵泡比率的影响。描述了一种改良的腹腔镜卵泡抽吸针。纯化的FSH/hMG卵巢刺激显著提高了平均血清雌二醇水平、排卵前卵泡数量，因此也提高了每个周期回收的卵母细胞总数。使用磨尖的针时，超声记录的每个排卵前卵泡以及每个抽吸卵泡回收的卵母细胞的平均比率显著增加。这两种改良方法均提高了我们IVF程序的成功率。
