Drug Ther Bull. 2014 Sep;52(9):105-8. doi: 10.1136/dtb.2014.9.0279.
For many years the only drugs licensed for the treatment of multiple sclerosis (MS) were administered by injection (interferon beta, glatiramer and ▼natalizumab). Recently, three oral drugs have become available. We have previously reviewed the use of ▼fingolimod for highly active relapsing-remitting MS1 and ▼teriflunomide for the management of relapsing-remitting MS in adults.2 Here, we review the evidence for ▼dimethyl fumarate (Tecfidera-Biogen Idec Ltd) for the treatment of adults with relapsing-remitting MS.
多年来，唯一获批用于治疗多发性硬化症（MS）的药物都是通过注射给药（干扰素β、格拉替雷和那他珠单抗）。最近，有三种口服药物可供使用。我们之前已经综述了芬戈莫德用于高度活动性复发缓解型MS的应用情况[1]以及特立氟胺用于成人复发缓解型MS管理的情况[2]。在此，我们综述富马酸二甲酯（Tecfidera - 百健艾迪公司）用于治疗成人复发缓解型MS的证据。
