Chapman Kristin Ow, Lelli Gary
Weill Cornell Medical Center , New York , USA.
Orbit. 2014 Dec;33(6):459-61. doi: 10.3109/01676830.2014.950289. Epub 2014 Sep 12.
To report a case of blepharoptosis in a patient with human immunodeficiency virus (HIV) on highly active antiretroviral therapy (HAART) with biopsy confirmed mitochondrial deletions consistent with HAART related myopathy.
A 51-year-old man with HIV demonstrated visually significant ptosis after being on HAART therapy for over 20 years.
Muscle tissue biopsy following blepharoplasty was analyzed and found to have significant mitochondrial deletions.
This patient represents a case of isolated ptosis consistent with acquired myopathy secondary to mitochondrial dysfunction without systemic manifestations otherwise seen in inherited mitochondrial disorders.
