Braun S A, Homey B, Gerber P A
Hautklinik des Universitätsklinikums Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Deutschland.
Hautarzt. 2014 Oct;65(10):848-50. doi: 10.1007/s00105-014-3509-5.
Ingenol mebutate is a novel cytotoxic drug extracted from the plant Euphorbia peplus. Since November 2012 it is approved in Germany for the treatment of superficial actinic keratoses. We report the successful treatment of Bowen disease with ingenol mebutate in a patient being treated with the multikinase inhibitor sunitinib for to metastatic clear cell renal carcinoma.
ingenol mebutate是一种从大戟科植物地锦草中提取的新型细胞毒性药物。自2012年11月起,它在德国被批准用于治疗浅表性光化性角化病。我们报告了一名正在接受多激酶抑制剂舒尼替尼治疗转移性透明细胞肾细胞癌的患者,使用ingenol mebutate成功治疗鲍恩病的病例。