Brannan Paul A, Anderson Heidi K, Kersten Robert C, Kulwin Dwight R
University of Cincinnati, Department of Ophthalmology, Cincinnati Eye Institute, Ohio 45242, USA.
Ophthalmic Plast Reconstr Surg. 2005 Jul;21(4):321-2. doi: 10.1097/01.iop.0000170421.07098.61.
We present a case of Bowen disease affecting the eyelid that was successfully treated with imiquimod. The clinical presentation, histopathology, and treatment of this case are presented. The tumor was treated with imiquimod for 3 months, leading to complete resolution of the disease both clinically and histopathologically. There was no evidence of recurrence 5 months after treatment cessation. Imiquimod was safely used on the eyelid in this case and may avoid extensive periocular tumor excision and reconstruction in Bowen disease.
我们报告一例用咪喹莫特成功治疗的眼睑鲍温病病例。本文介绍了该病例的临床表现、组织病理学及治疗情况。该肿瘤用咪喹莫特治疗3个月，临床和组织病理学上疾病均完全消退。停药5个月后无复发迹象。本病例中咪喹莫特在眼睑使用安全，在鲍温病中可避免广泛的眼周肿瘤切除及重建。
