Goh C L
Contact Clinic, Middle Road Hospital, Singapore.
Int J Dermatol. 1989 Jan-Feb;28(1):25-8. doi: 10.1111/j.1365-4362.1989.tb01304.x.
Of patients patch tested at a contact dermatitis clinic between 1985 and 1986, 22.5% (379/1685) had medicament sensitivity. The prevalence in men was 22.8% (193/847) and in women, 22.1% (186/838) (difference not significant). The rate appears to increase with age, 17.9% (216/1205) for patients less than 40 years old and 34.0% (163/480) for patients over 39 years old (difference, p less than 0.001). The differences in prevalence between Chinese (22.8%), Malay (21.3%), Indians (20.4%), and others (33.3%) were not statistically significant. Common sensitizers included neomycin (7.8%), proflavine (7.1%), clioquinol (4.3%), colophony (3.3%), and wool alcohol (2.7%). Proflavine sensitivity was significantly more common in men (9.9%) than women (4.2%) (p less than 0.001). Most dermatitis occurs on the limbs (upper limbs, 44.3%; lower limbs, 43.0%). Facial dermatitis was more common in women (37.4%) than men (19.2%) (difference not significant).
在1985年至1986年间于一家接触性皮炎诊所接受斑贴试验的患者中，22.5%（379/1685）有药物敏感性。男性患病率为22.8%（193/847），女性为22.1%（186/838）（差异不显著）。患病率似乎随年龄增长而增加，40岁以下患者为17.9%（216/1205），39岁以上患者为34.0%（163/480）（差异，p<0.001）。中国人（22.8%）、马来人（21.3%）、印度人（20.4%）和其他种族（33.3%）之间的患病率差异无统计学意义。常见的致敏原包括新霉素（7.8%）、硫酸普罗黄素（7.1%）、氯碘羟喹（4.3%）、松香（3.3%）和羊毛脂醇（2.7%）。硫酸普罗黄素敏感性在男性（9.9%）中显著高于女性（4.2%）（p<0.001）。大多数皮炎发生在四肢（上肢，44.3%；下肢，43.0%）。面部皮炎在女性（37.4%）中比男性（19.2%）更常见（差异不显著）。
