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经皮腔内肾动脉血管成形术后肾血管性高血压的治愈与改善

Cure and improvement of renovascular hypertension after percutaneous transluminal angioplasty of renal artery stenosis.

作者信息

Greminger P, Steiner A, Schneider E, Kuhlmann U, Steurer J, Siegenthaler W, Vetter W

机构信息

Department of Internal Medicine, University Hospital, Zurich, Switzerland.

出版信息

Nephron. 1989;51(3):362-6. doi: 10.1159/000185323.

Abstract

In the present study we report our long-term experience in 82 patients with renovascular hypertension (48 with atherosclerotic stenosis, 34 with fibromuscular dysplasia) who were followed up for a mean observation period of 23.6 months after percutaneous transluminal angioplasty (PTA) of renal artery stenosis. Our results show a highly significant decrease in mean systolic and diastolic blood pressure. Cure rates were slightly higher in patients with fibromuscular dysplasia (41% cured, 47% improved) than in those with atherosclerosis (23% cured, 54% improved). Kidney function significantly improved in patients with cure, remained stable in those with improvement and worsened in cases classified as unimproved. These results document the good long-term effect of PTA on blood pressure and kidney function in patients with renal artery stenosis.

摘要

在本研究中,我们报告了82例肾血管性高血压患者(48例为动脉粥样硬化性狭窄,34例为纤维肌发育不良)的长期随访经验,这些患者在肾动脉狭窄经皮腔内血管成形术(PTA)后平均观察期为23.6个月。我们的结果显示,平均收缩压和舒张压显著降低。纤维肌发育不良患者的治愈率(41%治愈,47%改善)略高于动脉粥样硬化患者(23%治愈,54%改善)。治愈患者的肾功能显著改善,改善患者的肾功能保持稳定,未改善患者的肾功能恶化。这些结果证明了PTA对肾动脉狭窄患者血压和肾功能具有良好的长期效果。

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