Khalid Roksana
University of Guelph, 50 Stone Rd East, Guelph, ON, Canada N1G 2W1.
Immunol Lett. 2014 Nov;162(1 Pt A):223-32. doi: 10.1016/j.imlet.2014.09.004. Epub 2014 Sep 16.
Autoimmune diseases, such as multiple sclerosis (MS), show a higher incidence rate in women compared to men, which may be due to differences in the immune system, sex hormones, or both. Furthermore a disruption in homeostasis within these systems appears to be contributing to the etiology of MS. These systems are also influenced by the environment and metabolic factors necessitating the adoption of a broader viewpoint of the contributing factors in MS in the search for effective therapeutics.
自身免疫性疾病，如多发性硬化症（MS），女性的发病率高于男性，这可能是由于免疫系统、性激素或两者的差异所致。此外，这些系统内稳态的破坏似乎也在MS的病因中起作用。这些系统还受到环境和代谢因素的影响，因此在寻找有效治疗方法时，有必要对MS的致病因素采取更广泛的观点。
