Baker P C
Napier Hospital.
N Z Med J. 1989 Mar 22;102(864):132-4.
Eighteen patients with old poliomyelitis were assessed in order to determine the incidence and severity of late complications. Sixty-one percent complained of new weakness, 83% fatigue and 17% muscle pain. After assessment 33% (six patients) were judged to have significant new weakness and muscle fatigue that could not be explained by other causes, and this group may have postpoliomyelitis progressive muscular atrophy or postpolio syndrome. Onset of symptoms was typically about 30 years after the acute illness; new weakness was relatively mild and progression was slow over many years. Clinically and pathologically this disorder is distinct from idiopathic motor neuron disease, and is not life threatening.
为了确定迟发性并发症的发生率和严重程度,对18例陈旧性脊髓灰质炎患者进行了评估。61%的患者主诉有新出现的肌无力,83%有疲劳感,17%有肌肉疼痛。评估后,33%(6例患者)被判定有明显的、无法用其他原因解释的新出现的肌无力和肌肉疲劳,这组患者可能患有脊髓灰质炎后进行性肌肉萎缩或小儿麻痹后遗症。症状通常在急性病后约30年出现;新出现的肌无力相对较轻,且在多年中进展缓慢。从临床和病理角度来看,这种疾病与特发性运动神经元病不同,不会危及生命。