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骶骨巨细胞瘤:采用扩大刮除术和髂腰融合术的保功能手术

Giant cell tumour of the sacrum: function-preserving surgery with extended curettage and ilio-lumbar fusion.

作者信息

Lakdawala Riaz H, Ahmad Tashfeen, Enam Syed A

出版信息

J Ayub Med Coll Abbottabad. 2013 Jul-Dec;25(3-4):94-7.

PMID:25226752
Abstract

Giant cell tumours of the sacrum pose a unique therapeutic challenge due to the inaccessibility of the tumour, significant intra-operative blood loss from extensive vascularity, high rate of local recurrence with conservative surgery, and loss of neurological function and mechanical instability with en-bloc excision. We present a case where successful outcome was achieved by tailoring treatment in consideration of the above issues. A 28 year old male diagnosed on biopsy to have giant cell tumour of the sacrum presented to us with low-back pain, left-sided S1 radiculopathy, ankle weakness and urinary incontinence. MRI showed a tumour involving the S1 and S2 vertebral segments, breaching the posterior cortex and compressing the neural elements. An angiographic tumour embolization was performed followed by surgery through a posterior approach whereby an extended curettage was done, carefully freeing the sacral nerve roots and abrading the bone using high-speed burr. An ilio-sacro-lumbar fusion was done employing iliolumbar instrumentation and bone grafting. Post-operatively, within a week the patient was ambulated with a lumbar corset. At 9 months follow-up, the patient was completely pain free, had no ankle weakness, and had normal continence. This treatment approach resulted in preservation of neurologic function and maintenance of spinal stability, thus the patient returned to full function.

摘要

由于骶骨巨细胞瘤位置难以触及、术中因丰富血供导致大量失血、保守手术局部复发率高以及整块切除会导致神经功能丧失和机械性不稳定,因此对其治疗具有独特的挑战性。我们报告了一例通过考虑上述问题来量身定制治疗方案从而取得成功结果的病例。一名28岁男性经活检诊断为骶骨巨细胞瘤,因腰背痛、左侧S1神经根病、踝关节无力和尿失禁前来就诊。磁共振成像(MRI)显示肿瘤累及S1和S2椎体节段,突破后皮质并压迫神经组织。先行血管造影肿瘤栓塞术,然后通过后路手术,进行扩大刮除术,小心游离骶神经根并用高速磨钻打磨骨质。采用髂腰内固定和植骨进行髂-骶-腰融合术。术后一周内,患者佩戴腰部束腹带可下地行走。在9个月的随访中,患者完全无痛,踝关节无无力症状,大小便失禁情况正常。这种治疗方法保留了神经功能并维持了脊柱稳定性,因此患者恢复了全部功能。

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