Mediannikov O, Fenollar F
URMITE, UMR CNRS 7278 - IRD 198 - INSERM, Aix Marseille Université, Marseille, France; Campus Universitaire IRD de Hann, Dakar, Senegal.
URMITE, UMR CNRS 7278 - IRD 198 - INSERM, Aix Marseille Université, Marseille, France; Campus Universitaire IRD de Hann, Dakar, Senegal.
Microb Pathog. 2014 Dec;77:142-8. doi: 10.1016/j.micpath.2014.09.008. Epub 2014 Sep 16.
Ticks are considered to be second worldwide to mosquitoes as vectors of human diseases and the most important vectors of disease-causing pathogens in domestic and wild animals. A number of emerging tick-borne pathogens are already discovered; however, the proportion of undiagnosed infectious diseases, especially in tropical regions, may suggest that there are still more pathogens associated with ticks. Moreover, the identification of bacteria associated with ticks may provide new tool for the control of ticks and tick-borne diseases. Described here molecular methods of screening of ticks, extensive use of modern culturomics approach, newly developed artificial media and different cell line cultures may significantly improve our knowledge about the ticks as the agents of human and animal pathology.
蜱虫被认为是全球仅次于蚊子的人类疾病传播媒介,也是家畜和野生动物致病病原体的最重要传播媒介。已经发现了许多新出现的蜱传病原体;然而,未确诊的传染病比例,尤其是在热带地区,可能表明仍有更多与蜱虫相关的病原体。此外,鉴定与蜱虫相关的细菌可能为控制蜱虫和蜱传疾病提供新工具。本文所述的蜱虫筛选分子方法、现代培养组学方法的广泛应用、新开发的人工培养基和不同的细胞系培养,可能会显著提高我们对蜱虫作为人类和动物病原体的认识。