Liang Yan-Fang, Lin Xiao-Yue, Ruan Jian-Bo, Zeng Jin-Cheng, Kang Dong-Ping, Wang Ling-Mei, Chen Can, Xu Jun-Fa, Wu Qiu-Liang
Department of Pathology, Taiping People's Hospital of Dongguan, Dongguan Hospital Affiliated to Medical College of Jinan University Dongguan 523905, China.
Department of Endocrinology, Taiping People's Hospital of Dongguan, Dongguan Hospital Affiliated to Medical College of Jinan University Dongguan 523905, China.
Int J Clin Exp Med. 2014 Aug 15;7(8):2377-9. eCollection 2014.
In this article, we described a mucoepidermoid carcinoma (MEC) located in the left forearm of a 39-year-old pregnant woman. Here, the patient had a superficial tip size apophysis nearly 3 years, which begin to sustained growth after pregnant in 2012, and stopped growth after childbirth. MEC is a rare malignant tumor. Previously reports showed it mainly arise from the salivary, bronchial, thyroid, breast, lacrimal gland and conjunctiva. Here, we reported a case of MEC arising from the forearm gland for the first time. Histological finding showed a cystic and solid tumor in fibrous tissue below the squamous epithelium, and some columnar or cuboidal mucous cells covering on the epidermal cells or mixed with epidermal cells included in the tumor tissues. Also, Focal hyperplasia epidermal cells with round or oval nucleus in center were distributed in small pieces but no keratosis. The tumor tissues were immunopositive for CEA, P63, ki-67 (10%), CK7 and CK5/6, and immunonegative for CK20 and GCDFP-15. This case is a low-grade MEC and the patient's postoperative recovery is smooth.
在本文中,我们描述了一例位于一名39岁孕妇左前臂的黏液表皮样癌(MEC)。在此,患者有一个浅表的小结节状隆起近3年,在2012年怀孕后开始持续生长,产后停止生长。MEC是一种罕见的恶性肿瘤。先前的报道显示它主要起源于唾液腺、支气管、甲状腺、乳腺、泪腺和结膜。在此,我们首次报道了一例起源于前臂腺体的MEC病例。组织学检查发现鳞状上皮下方的纤维组织中有一个囊实性肿瘤,肿瘤组织中有一些柱状或立方状黏液细胞覆盖在表皮细胞上或与表皮细胞混合。此外,局灶性增生的表皮细胞,细胞核圆形或椭圆形位于中央,呈小片状分布,但无角化。肿瘤组织CEA、P63、ki-67(10%)、CK7和CK5/6免疫阳性,CK20和GCDFP-15免疫阴性。该病例为低级别MEC,患者术后恢复顺利。