Silberstein Eldad, Krieger Yuval, Rosenberg Nir, Bogdanov-Berezovsky Alexander, Shoham Yaron, Saphier Oshra, Pagkalos Vasileios A, Joshua Ben-Zion
*Division of Plastic and Reconstructive Surgery, Soroka University Medical Center, Ben Gurion University, Beer Sheva, Israel; †Department of Chemical Engineering, Sami Shamoon College of Engineering, Beer-Sheva, Israel; and ‡Otolaringology and Head and Neck Surgery Division, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Ophthalmic Plast Reconstr Surg. 2016 Nov/Dec;32(6):e131-e132. doi: 10.1097/IOP.0000000000000314.
Invasive sinonasal mucormycosis is a rare fungal infection that usually occurs in immunocompromised or diabetic patients, and it is often fatal. The authors present a case of a woman patient suffering from systemic lupus erythematosus and diabetes mellitus treated with prednisone, presenting with a rapidly progressive rhino-orbital-cerebral mucormycosis. She was successfully treated with combined intravenous antifungal therapy and radical debridement followed by complex defect reconstruction with a free vertical rectus abdominis myocutaneous flap, tissue expander, and ophthalmic prosthesis.
侵袭性鼻-鼻窦毛霉菌病是一种罕见的真菌感染,通常发生在免疫功能低下或糖尿病患者中,且往往是致命的。作者报告了一例患有系统性红斑狼疮和糖尿病的女性患者,该患者接受泼尼松治疗,出现了迅速进展的鼻-眶-脑毛霉菌病。她通过联合静脉抗真菌治疗和根治性清创术,随后用游离垂直腹直肌肌皮瓣、组织扩张器和眼假体进行复杂的缺损重建,最终成功治愈。