Department of Neuroscience, Columbia University, New York, NY 10032, USA; Doctoral Program in Neurobiology and Behavior, Columbia University, New York, NY 10032, USA.
Department of Neuroscience, Columbia University, New York, NY 10032, USA; Kavli Institute for Brain Science, Columbia University, New York, NY 10032, USA.
Neuron. 2014 Sep 17;83(6):1231-4. doi: 10.1016/j.neuron.2014.09.003.
Whether morphology tailors functional properties of pyramidal neurons is not completely understood. In this issue of Neuron, Thome et al. (2014) show that, in hippocampal pyramidal neurons, axons frequently originate from basal dendrites rather than the soma, constituting a "privileged" channel for synaptic inputs located in these axon-carrying dendrites.
树突形态是否能塑造锥体神经元的功能特性尚不完全清楚。在本期《神经元》杂志中，Thome 等人（2014）发现，在海马锥体神经元中，轴突常常起源于基底树突而非胞体，这为位于携带轴突的树突中的突触输入构成了一条“优先”通道。
