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伴有腔静脉血栓形成、酷似肾细胞癌的肾盂尿路上皮癌

Renal pelvic urothelial carcinoma with vena caval thrombus mimicking renal cell carcinoma.

作者信息

Diaz Richilda Red, Kwon Jong Kyou, Lee Joo Yong, Nahm Ji Hae, Cho Kang Su, Ham Won Sik, Cho Nam Hoon, Choi Young Deuk

机构信息

Department of Urology, Urological Science Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Korean J Urol. 2014 Sep;55(9):624-7. doi: 10.4111/kju.2014.55.9.624. Epub 2014 Sep 5.

Abstract

A 61-year-old man presented with a right renal mass with a vena caval thrombus on computed tomography that was consistent with renal cell carcinoma. The results of routine laboratory examinations and urinalysis were within normal limits. Preoperative planning was critical owing to the presence of the vena caval thrombus. A radical nephrectomy, vena caval thrombectomy, and regional lymphadenectomy were done. The pathologic report was consistent with a high-grade, invasive urothelial carcinoma, with sarcomatoid differentiation involving the renal vein and inferior vena cava (Stage IV, T4N0M0). Thus, this was a rare case of upper tract urothelial carcinoma. Adjuvant chemotherapy with the methotrexate, vinblastine, doxorubicin, cisplatinum regimen is scheduled. To our knowledge, this is the first report in Korea of upper tract urothelial carcinoma of the sarcomatoid type with a vena caval thrombus.

摘要

一名61岁男性因计算机断层扫描显示右肾肿块伴腔静脉血栓就诊,该表现符合肾细胞癌。常规实验室检查和尿液分析结果均在正常范围内。由于存在腔静脉血栓,术前规划至关重要。遂进行了根治性肾切除术、腔静脉血栓切除术和区域淋巴结清扫术。病理报告显示为高级别浸润性尿路上皮癌,伴肉瘤样分化累及肾静脉和下腔静脉(IV期,T4N0M0)。因此,这是一例罕见的上尿路尿路上皮癌病例。计划采用甲氨蝶呤、长春花碱、多柔比星、顺铂方案进行辅助化疗。据我们所知,这是韩国首例伴有腔静脉血栓的肉瘤样型上尿路尿路上皮癌报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dfe/4165927/4dbfcb6579e7/kju-55-624-g001.jpg

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