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机器人辅助根治性肾切除术联合肝后腔静脉肿瘤血栓切除术(Ⅲ级)并扩大腹膜后淋巴结清扫术

Robotic-assisted Radical Nephrectomy With Retrohepatic Vena Caval Tumor Thrombectomy (Level III) Combined With Extended Retroperitoneal Lymph Node Dissection.

作者信息

Bratslavsky Gennady, Cheng Jed-Sian

机构信息

Department of Urology, SUNY Upstate Medical Center, Syracuse, NY.

Department of Urology, Massachusetts General Hospital, Boston, MA.

出版信息

Urology. 2015 Dec;86(6):1235-40. doi: 10.1016/j.urology.2015.05.042. Epub 2015 Aug 5.

Abstract

OBJECTIVE

To describe a case of robotic-assisted radical nephrectomy (RARN) with level III retrohepatic vena caval tumor thrombectomy (11 cm) and extended retroperitoneal lymph node dissection (RPLND) for renal cell carcinoma (RCC).

MATERIALS AND METHODS

A 52-year-old woman with a large right renal mass, 11-cm (level III) inferior vena cava (IVC) thrombus, with a negative metastatic workup presented to our clinic and was consented to undergo RARN. Intraoperative ultrasound confirmed the presence of tumor thrombus. After the division of the renal artery, control of the vena cava above and below the tumor thrombus as well as contralateral renal vein was obtained. A cavotomy was performed, the thrombus was removed, and the cavotomy was repaired. Additionally, an extended RPLND was performed with robotic assistance.

RESULTS

Total operative time was 6 hours and 6 minutes. Estimated blood loss was 1200 cc. The final pathology demonstrated an 8.5-cm, Fuhrman grade 3, clear cell RCC with sarcomatoid features and negative surgical margins. All 44 lymph nodes removed (hilar, paracaval, precaval, retrocaval, interaortocaval, and preaortic) were negative. Final staging was pT3b, N0, M0. The patient was discharged to home 36 hours postoperatively and experienced no perioperative or postoperative complications.

CONCLUSION

RARN with retrohepatic (level III) vena caval tumor thrombectomy and extended RPLND is technically feasible and has potential benefits. Robotic assistance may allow for improved intracorporal repair of the IVC and shortened recovery time, while maintaining oncologic principles.

摘要

目的

描述一例机器人辅助根治性肾切除术(RARN),术中进行Ⅲ级肝后腔静脉肿瘤血栓切除术(11厘米)及扩大腹膜后淋巴结清扫术(RPLND)治疗肾细胞癌(RCC)。

材料与方法

一名52岁女性,右肾有一个大肿块,下腔静脉(IVC)有11厘米(Ⅲ级)血栓,转移检查结果为阴性,前来我院就诊并同意接受RARN。术中超声证实存在肿瘤血栓。在切断肾动脉后,控制肿瘤血栓上下的腔静脉以及对侧肾静脉。进行腔静脉切开术,取出血栓,并修复腔静脉切开处。此外,在机器人辅助下进行扩大的RPLND。

结果

总手术时间为6小时6分钟。估计失血量为1200毫升。最终病理显示为一个8.5厘米、Fuhrman 3级、具有肉瘤样特征的透明细胞RCC,手术切缘阴性。切除的所有44个淋巴结(肾门、腔静脉旁、腔静脉前、腔静脉后、主动脉腔静脉间和主动脉前)均为阴性。最终分期为pT3b,N0,M0。患者术后36小时出院,未出现围手术期或术后并发症。

结论

RARN联合肝后(Ⅲ级)腔静脉肿瘤血栓切除术及扩大的RPLND在技术上是可行的,且具有潜在益处。机器人辅助可能有助于改善IVC的体内修复并缩短恢复时间,同时遵循肿瘤学原则。

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