Research Institute for Complex Issues of Cardiovascular Diseases under the Siberian Branch of the Russian Academy of Medical Sciences, Kemerovo, Russian Federation.
Research Institute for Complex Issues of Cardiovascular Diseases under the Siberian Branch of the Russian Academy of Medical Sciences, Kemerovo, Russian Federation.
Comput Biol Med. 2014 Nov;54:109-15. doi: 10.1016/j.compbiomed.2014.08.023. Epub 2014 Sep 1.
The development of computer-based 3D models of the aortic root is one of the most important problems in constructing the prostheses for transcatheter aortic valve implantation. In the current study, we analyzed data from 117 patients with and without aortic valve disease and computed tomography data from 20 patients without aortic valvular diseases in order to estimate the average values of the diameter of the aortic annulus and other aortic root parameters. Based on these data, we developed a 3D model of human aortic root with unique geometry. Furthermore, in this study we show that by applying different material properties to the aortic annulus zone in our model, we can significantly improve the quality of the results of finite element analysis. To summarize, here we present four 3D models of human aortic root with unique geometry based on computational analysis of ECHO and CT data. We suggest that our models can be utilized for the development of better prostheses for transcatheter aortic valve implantation.
基于计算机的主动脉根部 3D 模型的发展是构建经导管主动脉瓣植入术假体的最重要问题之一。在本研究中，我们分析了 117 例有或无主动脉瓣疾病的患者以及 20 例无主动脉瓣疾病的患者的 CT 数据，以估算主动脉瓣环直径和其他主动脉根部参数的平均值。基于这些数据，我们开发了具有独特几何形状的人体主动脉根部 3D 模型。此外，在本研究中，我们证明通过在模型中的主动脉瓣环区域应用不同的材料特性，我们可以显著提高有限元分析结果的质量。总之，在这里，我们根据 ECHO 和 CT 数据的计算分析，提出了四个具有独特几何形状的人体主动脉根部 3D 模型。我们建议我们的模型可用于开发更好的经导管主动脉瓣植入术假体。
