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Specific molecular mutation patterns delineate chronic neutrophilic leukemia, atypical chronic myeloid leukemia, and chronic myelomonocytic leukemia.

作者信息

Meggendorfer Manja, Haferlach Torsten, Alpermann Tamara, Jeromin Sabine, Haferlach Claudia, Kern Wolfgang, Schnittger Susanne

机构信息

MLL Munich Leukemia Laboratory, Germany

MLL Munich Leukemia Laboratory, Germany.

出版信息

Haematologica. 2014 Dec;99(12):e244-6. doi: 10.3324/haematol.2014.113159. Epub 2014 Sep 19.

DOI:10.3324/haematol.2014.113159
PMID:25239264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4258749/
Abstract
摘要

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本文引用的文献

1
The new genetics of chronic neutrophilic leukemia and atypical CML: implications for diagnosis and treatment.慢性中性粒细胞白血病和非典型 CML 的新遗传学：对诊断和治疗的影响。
Blood. 2013 Sep 5;122(10):1707-11. doi: 10.1182/blood-2013-05-500959. Epub 2013 Jul 29.
2
Prognostic score including gene mutations in chronic myelomonocytic leukemia.包含基因突变的慢性髓单核细胞白血病预后评分。
J Clin Oncol. 2013 Jul 1;31(19):2428-36. doi: 10.1200/JCO.2012.47.3314. Epub 2013 May 20.
3
Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML.致癌性 CSF3R 突变在慢性中性粒细胞白血病和非典型 CML 中的作用。
N Engl J Med. 2013 May 9;368(19):1781-90. doi: 10.1056/NEJMoa1214514.
4
SETBP1 mutations occur in 9% of MDS/MPN and in 4% of MPN cases and are strongly associated with atypical CML, monosomy 7, isochromosome i(17)(q10), ASXL1 and CBL mutations.SETBP1 突变发生在 9%的 MDS/MPN 和 4%的 MPN 病例中，与非典型 CML、单体 7、i(17)(q10) 等臂染色体、ASXL1 和 CBL 突变密切相关。
Leukemia. 2013 Sep;27(9):1852-60. doi: 10.1038/leu.2013.133. Epub 2013 Apr 30.
5
Mutations and prognosis in primary myelofibrosis.原发性骨髓纤维化中的突变与预后。
Leukemia. 2013 Sep;27(9):1861-9. doi: 10.1038/leu.2013.119. Epub 2013 Apr 26.
6
CSF3R T618I is a highly prevalent and specific mutation in chronic neutrophilic leukemia.CSF3R T618I 是慢性中性粒细胞白血病中一种高度普遍且特异性的突变。
Leukemia. 2013 Sep;27(9):1870-3. doi: 10.1038/leu.2013.122. Epub 2013 Apr 22.
7
Recurrent SETBP1 mutations in atypical chronic myeloid leukemia.非典型慢性髓性白血病中反复出现的 SETBP1 突变。
Nat Genet. 2013 Jan;45(1):18-24. doi: 10.1038/ng.2495. Epub 2012 Dec 9.
8
SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML).275 例慢性粒单核细胞白血病（CMML）患者中的 SRSF2 突变。
Blood. 2012 Oct 11;120(15):3080-8. doi: 10.1182/blood-2012-01-404863. Epub 2012 Aug 23.
9
Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases.ASXL1 基因突变与恶性髓系疾病谱中的不良预后相关。
J Hematol Oncol. 2012 Mar 21;5:12. doi: 10.1186/1756-8722-5-12.
10
Frequent pathway mutations of splicing machinery in myelodysplasia.骨髓增生异常综合征中剪接机制的频繁通路突变。
Nature. 2011 Sep 11;478(7367):64-9. doi: 10.1038/nature10496.