Suppr超能文献

双重麻烦:两种放射治疗的故事。

Double trouble: a tale of two radio-treatments.

作者信息

Ogbonnaya Ebere Sunny, Peev Nikolay, Nagaraja Sanjoy, Dardis Ronan

机构信息

Department of Neurosurgery, University Hospital Coventry and Warwickshire, Coventry, Coventry, UK.

Department of Neurosurgery, Salford Royal Hospital, Manchester, Manchester, UK.

出版信息

BMJ Case Rep. 2014 Sep 19;2014:bcr2014205922. doi: 10.1136/bcr-2014-205922.

Abstract

In recent years, an increasing number of patients are treated with radiation. In the early era of radiotherapy, which began soon after X-rays were discovered by Roentgen in 1895, tumours were irradiated with high doses of X-rays in a single fraction. The major initial setback was the damage caused to normal tissues; however, in recent times the use of stereotactic radiosurgery, which delivers high doses of radiation precisely to abnormal tissue targets while sparing the surrounding normal brain tissue, and particularly for surgically inaccessible tumours, has taken centre stage. Prophylactic whole brain radiation (in conjunction with aggressive chemotherapy) for childhood acute lymphoblastic leukaemia has been shown to improve patient survival, however, this is associated with complications in survivors. We report an interesting case of one of the longest survivors who has had double complications from radiotherapy-based interventions.

摘要

近年来,接受放疗的患者数量日益增多。在放射治疗的早期,即1895年伦琴发现X射线后不久便开始了,肿瘤接受单次大剂量X射线照射。最初的主要挫折是对正常组织造成的损伤;然而,近年来,立体定向放射外科的应用已成为焦点,它能将高剂量辐射精确地传递到异常组织靶点,同时 sparing周围正常脑组织,尤其适用于手术难以触及的肿瘤。对于儿童急性淋巴细胞白血病,预防性全脑放疗(联合积极化疗)已被证明可提高患者生存率,然而,这与幸存者的并发症相关。我们报告了一例有趣的病例,该患者是放疗相关干预导致双重并发症的最长幸存者之一。 (注:原文中“sparing”疑似拼写错误,可能是“sparing”,正确的可能是“sparing”,译为“ sparing”,保留周围正常脑组织。)

相似文献

1
Double trouble: a tale of two radio-treatments.双重麻烦:两种放射治疗的故事。
BMJ Case Rep. 2014 Sep 19;2014:bcr2014205922. doi: 10.1136/bcr-2014-205922.
2
Analysis of a Surgical Series of 21 Cerebral Radiation Necroses.21 例脑放射性坏死手术系列分析。
World Neurosurg. 2020 May;137:e462-e469. doi: 10.1016/j.wneu.2020.02.005. Epub 2020 Feb 10.

本文引用的文献

3
High-grade meningiomas: new avenues for drug treatment?高级别脑膜瘤:药物治疗的新途径?
Curr Opin Neurol. 2013 Dec;26(6):708-15. doi: 10.1097/WCO.0000000000000035.
5
Challenges with the diagnosis and treatment of cerebral radiation necrosis.脑放射性坏死的诊断和治疗挑战。
Int J Radiat Oncol Biol Phys. 2013 Nov 1;87(3):449-57. doi: 10.1016/j.ijrobp.2013.05.015. Epub 2013 Jun 19.
9

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验